Coronavirus disease 2019: scientific overview of the global pandemic

Coronavirus disease 2019 (COVID-19) is the disease caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genome sequencing of the virus revealed that it is a new zoonotic virus that might have evolved by jumping from bats to humans with one or more intermedia...

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Main Authors: A. Dey, R. Das, H.S. Misra, S. Uppal
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:New Microbes and New Infections
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297520301529
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author A. Dey
R. Das
H.S. Misra
S. Uppal
author_facet A. Dey
R. Das
H.S. Misra
S. Uppal
author_sort A. Dey
collection DOAJ
description Coronavirus disease 2019 (COVID-19) is the disease caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genome sequencing of the virus revealed that it is a new zoonotic virus that might have evolved by jumping from bats to humans with one or more intermediate hosts. The immediate availability of the sequence information in the public domain has accelerated the development of quantitative RT-PCR-based diagnostics. Numerous clinical trials have been prioritized globally for testing new vaccines and treatments against this disease. This review provides a broad insight into different aspects of COVID-19, an introduction to SARS-CoV-2 mitigation strategies and the present status of diagnostics and therapeutics.
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spelling doaj.art-e8ecae78daca468a945fb3782a584d3b2022-12-21T22:21:19ZengElsevierNew Microbes and New Infections2052-29752020-11-0138100800Coronavirus disease 2019: scientific overview of the global pandemicA. Dey0R. Das1H.S. Misra2S. Uppal3Molecular Genetics Section, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, IndiaMolecular Genetics Section, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, IndiaMolecular Genetics Section, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, IndiaMolecular Genetics Section, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, India; Corresponding author:S. Uppal, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.Coronavirus disease 2019 (COVID-19) is the disease caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genome sequencing of the virus revealed that it is a new zoonotic virus that might have evolved by jumping from bats to humans with one or more intermediate hosts. The immediate availability of the sequence information in the public domain has accelerated the development of quantitative RT-PCR-based diagnostics. Numerous clinical trials have been prioritized globally for testing new vaccines and treatments against this disease. This review provides a broad insight into different aspects of COVID-19, an introduction to SARS-CoV-2 mitigation strategies and the present status of diagnostics and therapeutics.http://www.sciencedirect.com/science/article/pii/S2052297520301529Cov-2COVID-19coronavirusdiagnosticsdiseaseglobal
spellingShingle A. Dey
R. Das
H.S. Misra
S. Uppal
Coronavirus disease 2019: scientific overview of the global pandemic
New Microbes and New Infections
Cov-2
COVID-19
coronavirus
diagnostics
disease
global
title Coronavirus disease 2019: scientific overview of the global pandemic
title_full Coronavirus disease 2019: scientific overview of the global pandemic
title_fullStr Coronavirus disease 2019: scientific overview of the global pandemic
title_full_unstemmed Coronavirus disease 2019: scientific overview of the global pandemic
title_short Coronavirus disease 2019: scientific overview of the global pandemic
title_sort coronavirus disease 2019 scientific overview of the global pandemic
topic Cov-2
COVID-19
coronavirus
diagnostics
disease
global
url http://www.sciencedirect.com/science/article/pii/S2052297520301529
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