Neuromuscular blocking agents in the intensive care unit

Neuromuscular blocking agents (NMBA) are a controversial therapeutic option in the approach to the critically ill patient. They are not innocuous, and the available evidence does not support their routine use in the intensive care unit. If necessary, monitoring protocols should be established to avo...

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Main Authors: Jonathan Rodríguez-Blanco, Tomás Rodríguez-Yanez, Jesús Daniel Rodríguez-Blanco, Amilkar José Almanza-Hurtado, María Cristina Martínez-Ávila, Diana Borré-Naranjo, María Camila Acuña Caballero, Carmelo Dueñas-Castell
Format: Article
Language:English
Published: SAGE Publishing 2022-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221128148
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author Jonathan Rodríguez-Blanco
Tomás Rodríguez-Yanez
Jesús Daniel Rodríguez-Blanco
Amilkar José Almanza-Hurtado
María Cristina Martínez-Ávila
Diana Borré-Naranjo
María Camila Acuña Caballero
Carmelo Dueñas-Castell
author_facet Jonathan Rodríguez-Blanco
Tomás Rodríguez-Yanez
Jesús Daniel Rodríguez-Blanco
Amilkar José Almanza-Hurtado
María Cristina Martínez-Ávila
Diana Borré-Naranjo
María Camila Acuña Caballero
Carmelo Dueñas-Castell
author_sort Jonathan Rodríguez-Blanco
collection DOAJ
description Neuromuscular blocking agents (NMBA) are a controversial therapeutic option in the approach to the critically ill patient. They are not innocuous, and the available evidence does not support their routine use in the intensive care unit. If necessary, monitoring protocols should be established to avoid residual relaxation, adverse effects, and associated complications. This narrative review discusses the current indications for the use of NMBA and the different tools for monitoring blockade in the intensive care unit. However, expanding the use of NMBA in critical settings merits the development of prospective studies.
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spelling doaj.art-e8ee8ec539dc4241a67bd45d0d1fbd792022-12-22T02:00:29ZengSAGE PublishingJournal of International Medical Research1473-23002022-09-015010.1177/03000605221128148Neuromuscular blocking agents in the intensive care unitJonathan Rodríguez-BlancoTomás Rodríguez-YanezJesús Daniel Rodríguez-BlancoAmilkar José Almanza-HurtadoMaría Cristina Martínez-ÁvilaDiana Borré-NaranjoMaría Camila Acuña CaballeroCarmelo Dueñas-CastellNeuromuscular blocking agents (NMBA) are a controversial therapeutic option in the approach to the critically ill patient. They are not innocuous, and the available evidence does not support their routine use in the intensive care unit. If necessary, monitoring protocols should be established to avoid residual relaxation, adverse effects, and associated complications. This narrative review discusses the current indications for the use of NMBA and the different tools for monitoring blockade in the intensive care unit. However, expanding the use of NMBA in critical settings merits the development of prospective studies.https://doi.org/10.1177/03000605221128148
spellingShingle Jonathan Rodríguez-Blanco
Tomás Rodríguez-Yanez
Jesús Daniel Rodríguez-Blanco
Amilkar José Almanza-Hurtado
María Cristina Martínez-Ávila
Diana Borré-Naranjo
María Camila Acuña Caballero
Carmelo Dueñas-Castell
Neuromuscular blocking agents in the intensive care unit
Journal of International Medical Research
title Neuromuscular blocking agents in the intensive care unit
title_full Neuromuscular blocking agents in the intensive care unit
title_fullStr Neuromuscular blocking agents in the intensive care unit
title_full_unstemmed Neuromuscular blocking agents in the intensive care unit
title_short Neuromuscular blocking agents in the intensive care unit
title_sort neuromuscular blocking agents in the intensive care unit
url https://doi.org/10.1177/03000605221128148
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