NF-kappaB mediates Gadd45beta expression and DNA demethylation in the hippocampus during fear memory formation.

NF-kappaB mediates Gadd45beta expression and DNA demethylation in the hippocampus during fear memory formation.

Gadd45-mediated DNA demethylation mechanisms have been implicated in the process of memory formation. However, the transcriptional mechanisms involved in the regulation of Gadd45 gene expression during memory formation remain unexplored. NF-kB (nuclear factor kappa-light-chain-enhancer of activated...

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Bibliographic Details
Main Authors: Timothy J Jarome, Anderson A. Butler, Jessica N. Nichols, Natasha L. Pacheco, Farah D. Lubin
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Hippocampus
Memory
nuclear factor kappa B
DNA demethylation
GADD45
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00054/full

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