Bibliometric analysis of publications on necroptosis from 2001 to 2021
Background: Necroptosis plays an important role in inflammation, cancer, and neurodegenerative diseases. In recent years, the number of studies related to necroptosis has increased and research has become increasingly in-depth. This study aimed to summarize the research conducted since 2001 to disco...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.946363/full |
| _version_ | 1811266312224112640 |
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| author | Yang Liu Yang Liu Xiaojiang Zhou Xiaojiang Zhou Fangfei Wang Fangfei Wang Cong Liu Cong Liu Jun Xie Jun Xie Le Guan Yong Xie Yong Xie |
| author_facet | Yang Liu Yang Liu Xiaojiang Zhou Xiaojiang Zhou Fangfei Wang Fangfei Wang Cong Liu Cong Liu Jun Xie Jun Xie Le Guan Yong Xie Yong Xie |
| author_sort | Yang Liu |
| collection | DOAJ |
| description | Background: Necroptosis plays an important role in inflammation, cancer, and neurodegenerative diseases. In recent years, the number of studies related to necroptosis has increased and research has become increasingly in-depth. This study aimed to summarize the research conducted since 2001 to discover hotspots and trends in the field of necroptosis.Methods: The Web of Science Core database was used to identify global publications on necroptosis from 2001 to 2021. Bibliometric analysis was performed using Rstudio, VOSviewer, and CiteSpace.Results: The number of publications related to necroptosis gradually increased from 2001 to 2021. Vandenabeele P had the most publications at 45. Yuan JY had the most citations at 5,901. Necroptosis research has been dominated by China and Chinese institutions. Cell Death and Disease had the highest number of related publications among the examined journals. Seven of the top 10 most cited papers had more than 500 citations. Necroptosis, cell death, autophagy, injury, cancer, activated B cell nuclear factor kappa-light chain enhancer, and oxidative stress were important keywords in keyword analysis. Recent research has increasingly focused on breast cancer, receptor-interacting serine/threonine protein kinase 1, modulation, pseudokinase mixed lineage kinase domain-like protein, membrane, protection, and cycle.Conclusion: Interest in necroptosis-related research continues to increase steadily, and there is close cooperation between countries and institutions in the field of necroptosis. The study of necroptosis-related molecules and mechanisms, and the relationship between necroptosis and cancer, may be hotspots and directions in future research. |
| first_indexed | 2024-04-12T20:40:59Z |
| format | Article |
| id | doaj.art-e8f57554dd984829a88683f1db24f71d |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-04-12T20:40:59Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-e8f57554dd984829a88683f1db24f71d2022-12-22T03:17:25ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-09-011010.3389/fcell.2022.946363946363Bibliometric analysis of publications on necroptosis from 2001 to 2021Yang Liu0Yang Liu1Xiaojiang Zhou2Xiaojiang Zhou3Fangfei Wang4Fangfei Wang5Cong Liu6Cong Liu7Jun Xie8Jun Xie9Le Guan10Yong Xie11Yong Xie12Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaJiangxi Clinical Research Center for Gastroenterology, Nanchang, Jiangxi, ChinaBackground: Necroptosis plays an important role in inflammation, cancer, and neurodegenerative diseases. In recent years, the number of studies related to necroptosis has increased and research has become increasingly in-depth. This study aimed to summarize the research conducted since 2001 to discover hotspots and trends in the field of necroptosis.Methods: The Web of Science Core database was used to identify global publications on necroptosis from 2001 to 2021. Bibliometric analysis was performed using Rstudio, VOSviewer, and CiteSpace.Results: The number of publications related to necroptosis gradually increased from 2001 to 2021. Vandenabeele P had the most publications at 45. Yuan JY had the most citations at 5,901. Necroptosis research has been dominated by China and Chinese institutions. Cell Death and Disease had the highest number of related publications among the examined journals. Seven of the top 10 most cited papers had more than 500 citations. Necroptosis, cell death, autophagy, injury, cancer, activated B cell nuclear factor kappa-light chain enhancer, and oxidative stress were important keywords in keyword analysis. Recent research has increasingly focused on breast cancer, receptor-interacting serine/threonine protein kinase 1, modulation, pseudokinase mixed lineage kinase domain-like protein, membrane, protection, and cycle.Conclusion: Interest in necroptosis-related research continues to increase steadily, and there is close cooperation between countries and institutions in the field of necroptosis. The study of necroptosis-related molecules and mechanisms, and the relationship between necroptosis and cancer, may be hotspots and directions in future research.https://www.frontiersin.org/articles/10.3389/fcell.2022.946363/fullnecroptosisbibliometric analysishotspottrendcancer |
| spellingShingle | Yang Liu Yang Liu Xiaojiang Zhou Xiaojiang Zhou Fangfei Wang Fangfei Wang Cong Liu Cong Liu Jun Xie Jun Xie Le Guan Yong Xie Yong Xie Bibliometric analysis of publications on necroptosis from 2001 to 2021 Frontiers in Cell and Developmental Biology necroptosis bibliometric analysis hotspot trend cancer |
| title | Bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| title_full | Bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| title_fullStr | Bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| title_full_unstemmed | Bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| title_short | Bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| title_sort | bibliometric analysis of publications on necroptosis from 2001 to 2021 |
| topic | necroptosis bibliometric analysis hotspot trend cancer |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2022.946363/full |
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