Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020
BackgroundPrevious studies suggested that gut dysbacteriosis may promote the occurrence of chronic kidney disease (CKD), and probiotic, prebiotic, or yogurt supplements may alleviate CKD progression. This study aims to examine the association between probiotic, prebiotic, or yogurt supplements and t...
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1058238/full |
| _version_ | 1797978457480626176 |
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| author | Xiaoxian Liu Wenyan Gao Jie Yang Genxiang Mao Hong Lu Wenmin Xing |
| author_facet | Xiaoxian Liu Wenyan Gao Jie Yang Genxiang Mao Hong Lu Wenmin Xing |
| author_sort | Xiaoxian Liu |
| collection | DOAJ |
| description | BackgroundPrevious studies suggested that gut dysbacteriosis may promote the occurrence of chronic kidney disease (CKD), and probiotic, prebiotic, or yogurt supplements may alleviate CKD progression. This study aims to examine the association between probiotic, prebiotic, or yogurt supplements and the risk of CKD using the data from NHANES.MethodsThis study was designed to prospectively search data from the National Health and Nutrition Examination Survey (NHANES) (2011–2020). We examined dietary supplements and prescription medication labels to identify probiotic, or prebiotic product, and yogurt consumption during the dietary interview. The diagnosis of CKD was determined by the value of glomerular filtration rate (eGFR) and albumin creatinine ratio (ACR).ResultsThe study enrolled a total of 6,522 individuals. The prevalence of CKD was lower in the probiotic, prebiotic, or yogurt consumption group [age-adjusted odds ratio (OR): 0.77, 95% CI: 0.62–0.95, P = 0.02; multivariable-adjusted OR: 0.86, 95% CI: 0.69–1.07, P = 0.05]. Furthermore, 32% reduced risk was observed in the older group aged 55 years or older, and 32% reduced risk was also observed in the female population. Probiotic, or prebiotic, or yogurt supplements was associated a 12% reduction in moderate risk of CKD and an 11% reduction in very high risk of CKD.ConclusionOur results suggest that probiotic, prebiotic, or yogurt supplements may contribute to the prevention of CKD and relieve its progression risk, especially in the female population and older population who were aged 55 years or older. |
| first_indexed | 2024-04-11T05:23:17Z |
| format | Article |
| id | doaj.art-e8f6b722c29b48a48facbde666fdf861 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T05:23:17Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-e8f6b722c29b48a48facbde666fdf8612022-12-23T14:22:34ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10582381058238Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020Xiaoxian Liu0Wenyan Gao1Jie Yang2Genxiang Mao3Hong Lu4Wenmin Xing5Department of Nephrology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaSchool of Pharmacy, Hangzhou Medical College, Hangzhou, ChinaDepartment of Nephrology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, ChinaZhejiang Provincial Key Laboratory of Geriatrics, Department of Geriatrics, Zhejiang Hospital, Hangzhou, ChinaSchool of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, ChinaZhejiang Provincial Key Laboratory of Geriatrics, Department of Geriatrics, Zhejiang Hospital, Hangzhou, ChinaBackgroundPrevious studies suggested that gut dysbacteriosis may promote the occurrence of chronic kidney disease (CKD), and probiotic, prebiotic, or yogurt supplements may alleviate CKD progression. This study aims to examine the association between probiotic, prebiotic, or yogurt supplements and the risk of CKD using the data from NHANES.MethodsThis study was designed to prospectively search data from the National Health and Nutrition Examination Survey (NHANES) (2011–2020). We examined dietary supplements and prescription medication labels to identify probiotic, or prebiotic product, and yogurt consumption during the dietary interview. The diagnosis of CKD was determined by the value of glomerular filtration rate (eGFR) and albumin creatinine ratio (ACR).ResultsThe study enrolled a total of 6,522 individuals. The prevalence of CKD was lower in the probiotic, prebiotic, or yogurt consumption group [age-adjusted odds ratio (OR): 0.77, 95% CI: 0.62–0.95, P = 0.02; multivariable-adjusted OR: 0.86, 95% CI: 0.69–1.07, P = 0.05]. Furthermore, 32% reduced risk was observed in the older group aged 55 years or older, and 32% reduced risk was also observed in the female population. Probiotic, or prebiotic, or yogurt supplements was associated a 12% reduction in moderate risk of CKD and an 11% reduction in very high risk of CKD.ConclusionOur results suggest that probiotic, prebiotic, or yogurt supplements may contribute to the prevention of CKD and relieve its progression risk, especially in the female population and older population who were aged 55 years or older.https://www.frontiersin.org/articles/10.3389/fnut.2022.1058238/fullprobioticsprebioticyogurtchronic kidney diseaseNHANES findings |
| spellingShingle | Xiaoxian Liu Wenyan Gao Jie Yang Genxiang Mao Hong Lu Wenmin Xing Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 Frontiers in Nutrition probiotics prebiotic yogurt chronic kidney disease NHANES findings |
| title | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 |
| title_full | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 |
| title_fullStr | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 |
| title_full_unstemmed | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 |
| title_short | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010–2020 |
| title_sort | association between probiotic prebiotic and yogurt consumption and chronic kidney disease the nhanes 2010 2020 |
| topic | probiotics prebiotic yogurt chronic kidney disease NHANES findings |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1058238/full |
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