National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom
Introduction Methodologically robust clinical trials are required to improve neonatal care and reduce unwanted variations in practice. Previous neonatal research prioritisation processes have identified important research themes rather than specific research questions amenable to clinical trials. Pr...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/9/e061330.full |
| _version_ | 1811195503810969600 |
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| author | Jon Dorling James Webbe William D Carroll James P Boardman Helen Mactier Cheryl Battersby Elaine M Boyle Pollyanna Hardy Emma Johnston Katie Gallagher Katie Evans Kate Dinwiddy Claire Marcroft |
| author_facet | Jon Dorling James Webbe William D Carroll James P Boardman Helen Mactier Cheryl Battersby Elaine M Boyle Pollyanna Hardy Emma Johnston Katie Gallagher Katie Evans Kate Dinwiddy Claire Marcroft |
| author_sort | Jon Dorling |
| collection | DOAJ |
| description | Introduction Methodologically robust clinical trials are required to improve neonatal care and reduce unwanted variations in practice. Previous neonatal research prioritisation processes have identified important research themes rather than specific research questions amenable to clinical trials. Practice-changing trials require well-defined research questions, commonly organised using the Population, Intervention, Comparison, Outcome (PICO) structure. By narrowing the scope of research priorities to those which can be answered in clinical trials and by involving a wide range of different stakeholders, we aim to provide a robust and transparent process to identify and prioritise research questions answerable within the National Healthcare System to inform future practice-changing clinical trials.Methods and analysis A steering group comprising parents, doctors, nurses, allied health professionals, researchers and representatives from key organisations (Neonatal Society, British Association of Perinatal Medicine, Neonatal Nurses Association and Royal College of Paediatrics and Child Health) was identified to oversee this project. We will invite submissions of research questions formatted using the PICO structure from the following stakeholder groups using an online questionnaire: parents, patients, healthcare professionals and academic researchers. Unanswered, non-duplicate research questions will be entered into a three-round eDelphi survey of all stakeholder groups. Research questions will be ranked by mean aggregate scores.Ethics and dissemination The final list of prioritised research questions will be disseminated through traditional academic channels, directly to key stakeholder groups through representative organisations and on social media. The outcome of the project will be shared with key research organisations such as the National Institute for Health Research. Research ethics committee approval is not required. |
| first_indexed | 2024-04-12T00:44:23Z |
| format | Article |
| id | doaj.art-e8faa17ef3b445c9ab806a1796315379 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-12T00:44:23Z |
| publishDate | 2022-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-e8faa17ef3b445c9ab806a17963153792022-12-22T03:54:56ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2022-061330National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United KingdomJon Dorling0James Webbe1William D Carroll2James P Boardman3Helen Mactier4Cheryl Battersby5Elaine M Boyle6Pollyanna Hardy7Emma Johnston8Katie Gallagher9Katie Evans10Kate Dinwiddy11Claire Marcroft12Neonatal Medicine, University Hospital Southampton, Southampton, UKNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UKDepartment of Paediatric Respiratory Medicine, University Hospitals of North Midlands, Stoke-on-Trent, UKMRC Centre for Reproductive Health, The University of Edinburgh, Edinburgh, UKNeonatal Medicine, University of Glasgow, Glasgow, UKNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UKNeonatal Medicine, Department of Health Sciences, University of Leicester, Leicester, UKNational Perinatal Epidemiology Unit, Clinical Trials Unit, University of Oxford, Oxford, UKParents and Families Engagement Lead, Thames Valley and Wessex Operational Deliveries Network, Thames Valley and Wessex, UKChild and Adolescent Health, University College London, EGA Institute for Women`s Health, London, UKNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UKChief Executive of British Association of Perinatal Medicine, London, UKPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UKIntroduction Methodologically robust clinical trials are required to improve neonatal care and reduce unwanted variations in practice. Previous neonatal research prioritisation processes have identified important research themes rather than specific research questions amenable to clinical trials. Practice-changing trials require well-defined research questions, commonly organised using the Population, Intervention, Comparison, Outcome (PICO) structure. By narrowing the scope of research priorities to those which can be answered in clinical trials and by involving a wide range of different stakeholders, we aim to provide a robust and transparent process to identify and prioritise research questions answerable within the National Healthcare System to inform future practice-changing clinical trials.Methods and analysis A steering group comprising parents, doctors, nurses, allied health professionals, researchers and representatives from key organisations (Neonatal Society, British Association of Perinatal Medicine, Neonatal Nurses Association and Royal College of Paediatrics and Child Health) was identified to oversee this project. We will invite submissions of research questions formatted using the PICO structure from the following stakeholder groups using an online questionnaire: parents, patients, healthcare professionals and academic researchers. Unanswered, non-duplicate research questions will be entered into a three-round eDelphi survey of all stakeholder groups. Research questions will be ranked by mean aggregate scores.Ethics and dissemination The final list of prioritised research questions will be disseminated through traditional academic channels, directly to key stakeholder groups through representative organisations and on social media. The outcome of the project will be shared with key research organisations such as the National Institute for Health Research. Research ethics committee approval is not required.https://bmjopen.bmj.com/content/12/9/e061330.full |
| spellingShingle | Jon Dorling James Webbe William D Carroll James P Boardman Helen Mactier Cheryl Battersby Elaine M Boyle Pollyanna Hardy Emma Johnston Katie Gallagher Katie Evans Kate Dinwiddy Claire Marcroft National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom BMJ Open |
| title | National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom |
| title_full | National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom |
| title_fullStr | National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom |
| title_full_unstemmed | National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom |
| title_short | National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom |
| title_sort | national priority setting partnership using a delphi consensus process to develop neonatal research questions suitable for practice changing randomised trials in the united kingdom |
| url | https://bmjopen.bmj.com/content/12/9/e061330.full |
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