The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study

The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study

Abstract Background Pepsinogen C (PGC) is expressed in chief cells, fundic mucous neck cells, and pyloric gland cells of gastric epithelium and also in breast, prostate, lung, and seminal vesicles. Methods We explored the clinicopathological and prognostic significances of PGC mRNA using pathologica...

Full description

Bibliographic Details
Main Authors:	Ying E., Qian Yu, Tao Sun, Hang Xue, Xue-rong Zhao, Hua-chuan Zheng
Format:	Article
Language:	English
Published:	BMC 2023-06-01
Series:	BMC Cancer
Subjects:	Transgenic mouse Pepsinogen C PTEN Gastric cancer Breast cancer Chief cell
Online Access:	https://doi.org/10.1186/s12885-023-11020-z

Similar Items

A pepsinogen from dog stomach /
by: 440992 Twining, Sally S., et al.

The role of pepsinogen test among the patients with gastric cancer.
by: Mahmood R. AL-Robeyii, et al.
Published: (2010-07-01)

Clinical value of serum pepsinogen,gastrin 17 and Helicobacter pylori IgG antibody in primary screening of gastric diseases
by: LI Nana, QI Tao, ZHU Liming
Published: (2022-08-01)

Polymorphisms in Pepsinogen C and miRNA Genes Associate with High Serum Pepsinogen II in Gastric Cancer Patients
by: Valli De Re, et al.
Published: (2021-01-01)

Assessment of Serum Pepsinogens with and without Co-Testing with Gastrin-17 in Gastric Cancer Risk Assessment—Results from the GISTAR Pilot Study
by: Claudia Robles, et al.
Published: (2022-07-01)

Association of serum pepsinogens and gastrin-17 with Helicobacter pylori infection assessed by urea breath test
by: Jun-peng Zhou, et al.
Published: (2022-08-01)

Gastric mucosa structure in patients with different serum pepsinogen levels and ratios
by: V. V. Tsukanov, et al.
Published: (2018-10-01)

Pepsinogen ratio and brachial-ankle pulse wave velocity: a cross-sectional study on their interrelationship in atherosclerosis
by: Yuexi Li, et al.
Published: (2023-11-01)

Factors Associated with False Negative Results in Serum Pepsinogen Testing for Precancerous Gastric Lesions in a European Population in the GISTAR Study
by: Danute Razuka-Ebela, et al.
Published: (2022-05-01)

Development of a Radioimmunoassay for Bovine Pepsinogen A
by: D. I. Sidikou, et al.
Published: (2005-04-01)

Correlation between Interleukin-17, High Sensitivity C-Reactive Protein and Pepsinogen in <i>Helicobacter pylori</i> Infected Gastritis
by: Jeanne Winarta, et al.
Published: (2024-01-01)

The Serum Pepsinogen Level of Dairy Cows with Gastrointestinal Disorders
by: Ali HAJIMOHAMMADI, et al.
Published: (2017-01-01)

Combination of Serum Test and Questionnaire in Early Gastric Cancer Screening
by: Qiang Li, et al.
Published: (2022-08-01)

Serum pepsinogen level as a biomarker for atrophy, reflux esophagitis, and gastric cancer screening in Indonesia
by: Muhammad Miftahussurur, et al.
Published: (2022-01-01)

Pepsinogen testing for evaluation of the success of Helicobacter pylori eradication at 4 weeks after completion of therapy
by: Marcis Leja, et al.
Published: (2014-01-01)

A DSC Test for the Early Detection of Neoplastic Gastric Lesions in a Medium-Risk Gastric Cancer Area
by: Valli De Re, et al.
Published: (2023-02-01)

Endoscopic Resection for Gastric Adenocarcinoma of the Fundic Gland Type: A Case Series
by: Hwa Jin Lee, et al.
Published: (2023-06-01)

Increased Prevalence of Autoimmune Gastritis in Patients with a Gastric Precancerous Lesion
by: Xiaopei Guo, et al.
Published: (2023-09-01)

Performing the ABC Method Twice for Gastric Cancer Risk Stratification: A Retrospective Study Based on Data from a Large-Scale Screening Facility
by: Satoru Mizutani, et al.
Published: (2023-03-01)

CDX2 Inhibits Invasion and Migration of Gastric Cancer Cells by Phosphatase and Tensin Homologue Deleted from Chromosome 10/Akt Signaling Pathway
by: Yong-Qiang Liu, et al.
Published: (2015-01-01)

PTEN Protein Loss and Loss-of-Function Mutations in Gastric Cancers: The Relationship with Microsatellite Instability, EBV, HER2, and PD-L1 Expression
by: Binnari Kim, et al.
Published: (2020-06-01)

Research progress on the role of gastric microecology in gastric carcinogenesis
by: JI Ruo-yu, CAO Xin-yuan, ZHANG Yi-zhen, WANG Qiang, WU Xi, YANG Ying-yun, YANG Ai-ming
Published: (2022-12-01)

Serum Pepsinogens Combined with New Biomarkers Testing Using Chemiluminescent Enzyme Immunoassay for Non-Invasive Diagnosis of Atrophic Gastritis: A Prospective, Multicenter Study
by: Nicolas Chapelle, et al.
Published: (2022-03-01)

The role of gastric microecological dysbiosis in gastric carcinogenesis
by: Hui Huang, et al.
Published: (2023-07-01)

Serum pepsinogen level and abomasal ulcerations in experimental abomasal displacement in sheep
by: A. Hajimohammadi, et al.
Published: (2010-07-01)

Kajian mengenai beberapa aspek fizikal bagi tindakbalas pemangkinan pepsin terhadap polipeptida /
by: Zahariah Hujan, author, et al.
Published: (1987)

Potentialities of a serological method in diagnosis of atrophic gastritis
by: S I Pimanov, et al.
Published: (2008-02-01)

Helicobacter pylori infection, serum pepsinogens as markers of atrophic gastritis, and leukocyte telomere length: a population-based study
by: Khitam Muhsen, et al.
Published: (2019-07-01)

Detouring the Undesired Route of Helicobacter pylori-Induced Gastric Carcinogenesis
by: Ki Baik Hahm, et al.
Published: (2011-07-01)

Editorial: The role of Helicobacter pylori in gastric carcinogenesis
by: Javier Torres, et al.
Published: (2023-06-01)

PTEN Expression Was Significantly Associated with PD-L1 Score but Not with EBV Infection in Gastric Cancer
by: Cao D, et al.
Published: (2022-09-01)

Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics
by: Anthi Kolokotroni, et al.
Published: (2023-08-01)

Iroquois Family Genes in Gastric Carcinogenesis: A Comprehensive Review
by: Everton Cruz dos Santos, et al.
Published: (2023-03-01)

The AKT1E17K Allele Promotes Breast Cancer in Mice
by: Donatella Malanga, et al.
Published: (2022-05-01)

Improving Expression of Pepsinogen A from <i>Homo sapiens</i> in <i>Aspergillus niger</i> by Using a Multi-Copy Gene Knock-in Strategy
by: Jie Chen, et al.
Published: (2023-05-01)

Characterisation of the immune repertoire of a humanised transgenic mouse through immunophenotyping and high-throughput sequencing
by: Eve Richardson, et al.
Published: (2023-03-01)

RELATED CHANGES OF SERUM CYTOKINES AND MARKERS OF THE SECRETORY ACTIVITY OF THE GASTRIC MUCOSA AT ULCEROUS PROCESS
by: L. V. Matveeva, et al.
Published: (2014-07-01)

Metformin exhibits antineoplastic effects on Pten-deficient endometrial cancer by interfering with TGF-β and p38/ERK MAPK signalling
by: Anna Ruiz-Mitjana, et al.
Published: (2023-12-01)

The Diagnostic Value of Anti-Parietal Cell and Intrinsic Factor Antibodies, Pepsinogens, and Gastrin-17 in Corpus-Restricted Atrophic Gastritis
by: Petra Kriķe, et al.
Published: (2022-11-01)

Gastric metastasis of breast cancer: A frequent mimicker of primary gastric cancer in breast cancer patients
by: Sara vanBekkum, et al.
Published: (2022-11-01)