Quantitative analysis of mitochondrial morphologies in human induced pluripotent stem cells for Leigh syndrome

Quantitative analysis of mitochondrial morphologies in human induced pluripotent stem cells for Leigh syndrome

Mitochondria are dynamic organelles with wide range of morphologies contributing to regulating different signaling pathways and several cellular functions. Leigh syndrome (LS) is a classic pediatric mitochondrial disorder characterized by complex and variable clinical pathologies, and primarily affe...

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Bibliographic Details
Main Authors:	Fibi Meshrkey, Ana Cabrera Ayuso, Raj R. Rao, Shilpa Iyer
Format:	Article
Language:	English
Published:	Elsevier 2021-12-01
Series:	Stem Cell Research
Subjects:	Mitochondrial dynamics Mitochondrial morphology Mitochondrial disorders Mitochondrial membrane potential Human induced pluripotent stem cells Leigh syndrome
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506121004190

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