Protein phosphatase 1 regulatory inhibitor subunit 14C promotes triple‐negative breast cancer progression via sustaining inactive glycogen synthase kinase 3 beta

Protein phosphatase 1 regulatory inhibitor subunit 14C promotes triple‐negative breast cancer progression via sustaining inactive glycogen synthase kinase 3 beta

Abstract Triple‐negative breast cancer (TNBC) is fast‐growing and highly metastatic with the poorest prognosis among the breast cancer subtypes. Inactivation of glycogen synthase kinase 3 beta (GSK3β) plays a vital role in the aggressiveness of TNBC; however, the underlying mechanism for sustained G...

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Bibliographic Details
Main Authors: Yunting Jian, Lingzhi Kong, Hongyi Xu, Yawei Shi, Xinjian Huang, Wenjing Zhong, Shumei Huang, Yue Li, Dongni Shi, Yunyun Xiao, Muwen Yang, Siqi Li, Xiangfu Chen, Ying Ouyang, Yameng Hu, Xin Chen, Libing Song, Runyi Ye, Weidong Wei
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical and Translational Medicine
Subjects:
GSK3β
PPP1R14C
PRKCI
TNBC
Online Access:https://doi.org/10.1002/ctm2.725

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