TRAP-induced PAR1 expression with its mechanism during AMI in a rat model

TRAP-induced PAR1 expression with its mechanism during AMI in a rat model

Abstract Background and objective Protease-activated receptor 1 (PAR1) is crucial in individuals with acute myocardial infarction (AMI). The continuous and prompt PAR1 activation mainly dependent on PAR1 trafficking is essential for the role of PAR1 during AMI in which cardiomyocytes are in hypoxia....

Full description

Bibliographic Details
Main Authors: Ani Wang, Xinyuan Gu, Chunyang Wang, Yanhui Li, Fuhong Deng, Jie Fang, Naxia Chen, Qifu Li, Lilong Tang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cardiovascular Disorders
Subjects:
PAR1
Rab11
Cardiomyocytes
Hypoxia
Cardiac function
AMI
Online Access:https://doi.org/10.1186/s12872-023-03118-w

Similar Items

Similar Items