Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)

This article describes several clinical cases of acute ischemic stroke among patients suffering from essential thrombocytemia. Ambiguity of etiological factors of stroke is demonstrated among patients with this pathology. Thrombocytosis and high allele load in the Jak2 gene play an important role (e...

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Main Authors: M M TANASHYAN, P I KUZNETSOVA, A A RASKURAZHEV, I N SUBORTSEVA, A L MELIKYAN
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2018-07-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32804/pdf
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author M M TANASHYAN
P I KUZNETSOVA
A A RASKURAZHEV
I N SUBORTSEVA
A L MELIKYAN
author_facet M M TANASHYAN
P I KUZNETSOVA
A A RASKURAZHEV
I N SUBORTSEVA
A L MELIKYAN
author_sort M M TANASHYAN
collection DOAJ
description This article describes several clinical cases of acute ischemic stroke among patients suffering from essential thrombocytemia. Ambiguity of etiological factors of stroke is demonstrated among patients with this pathology. Thrombocytosis and high allele load in the Jak2 gene play an important role (even with normal platelet count) in progression of cerebrovascular disease. Also the question of effectiveness of preventive and etiological therapy is considered.
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spelling doaj.art-e904a28fb7a14817815d927773c311092022-12-22T01:56:16Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422018-07-0190710210410.26442/terarkh2018907102-10429556Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)M M TANASHYAN0P I KUZNETSOVA1A A RASKURAZHEV2I N SUBORTSEVA3A L MELIKYAN4Research Center of NeurologyResearch Center of NeurologyResearch Center of NeurologyNational Research Center of HematologyNational Research Center of HematologyThis article describes several clinical cases of acute ischemic stroke among patients suffering from essential thrombocytemia. Ambiguity of etiological factors of stroke is demonstrated among patients with this pathology. Thrombocytosis and high allele load in the Jak2 gene play an important role (even with normal platelet count) in progression of cerebrovascular disease. Also the question of effectiveness of preventive and etiological therapy is considered.https://ter-arkhiv.ru/0040-3660/article/viewFile/32804/pdfacute ischemic strokecerebrovascular diseasemyeloproliferative disordershaemotologyendothelial dysfunctionblood coagulation systemthrombosis
spellingShingle M M TANASHYAN
P I KUZNETSOVA
A A RASKURAZHEV
I N SUBORTSEVA
A L MELIKYAN
Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
Терапевтический архив
acute ischemic stroke
cerebrovascular disease
myeloproliferative disorders
haemotology
endothelial dysfunction
blood coagulation system
thrombosis
title Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
title_full Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
title_fullStr Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
title_full_unstemmed Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
title_short Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases)
title_sort acute ischemic stroke in the setting of essential thrombocytemia clinical cases
topic acute ischemic stroke
cerebrovascular disease
myeloproliferative disorders
haemotology
endothelial dysfunction
blood coagulation system
thrombosis
url https://ter-arkhiv.ru/0040-3660/article/viewFile/32804/pdf
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