Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.
The seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound identified. For the stem bark oil obtained during...
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MDPI AG
2014-04-01
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| 丛编: | Molecules |
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| 在线阅读: | http://www.mdpi.com/1420-3049/19/4/4560 |
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| author | Fabiana B. Furtado Francisco J. T. de Aquino Evandro A. Nascimento Carla de M. Martins Sérgio A. L. de Morais Roberto Chang Luís C. S. Cunha Luís F. Leandro Carlos H. G. Martins Mário M. Martins Claudio V. da Silva Fabrício C. Machado Alberto de Oliveira |
| author_facet | Fabiana B. Furtado Francisco J. T. de Aquino Evandro A. Nascimento Carla de M. Martins Sérgio A. L. de Morais Roberto Chang Luís C. S. Cunha Luís F. Leandro Carlos H. G. Martins Mário M. Martins Claudio V. da Silva Fabrício C. Machado Alberto de Oliveira |
| author_sort | Fabiana B. Furtado |
| collection | DOAJ |
| description | The seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound identified. For the stem bark oil obtained during the rainy season, in addition to terpenoids (26.63%), a large amount of fatty acids (46.84%) were identified, in particular palmitic acid (25.40%). Regarding the leaves’ essential oil obtained in the dry season, esters (42.35%) were the main components. The main ester present was (Z)-hex-3-enyl benzoate (10.15%) and the major compound of this oil was (Z)-hex-3-en-1-ol (14.23%). Terpenoids (33.84%), long-chain alkanes (27.04%) and fatty acids (21.72%) were the main components of the essential oil from leaves in the rainy season. Phytol (33.21%), nonacosane (21.95%) and palmitic acid (15.20%) were the major compounds identified. The antimicrobial activity against aerobic and anaerobic oral bacteria was evaluated by the microdilution broth method and cytotoxic activity was carried out with Vero cells. The essential oils from the rainy season showed a better inhibition of the bacterial growth with Minimal Inhibitory Concentrations (MIC) values of 25 or 50 µg·mL−1 for aerobic bacteria, and high selectivity against bacteria was observed. The large amount of fatty acids in rainy season oils may be related to the better inhibitory effects observed. |
| first_indexed | 2024-12-12T21:35:04Z |
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| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T21:35:04Z |
| publishDate | 2014-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-e906250f939e477c8cc7461476e445f72022-12-22T00:11:12ZengMDPI AGMolecules1420-30492014-04-011944560457710.3390/molecules19044560molecules19044560Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.Fabiana B. Furtado0Francisco J. T. de Aquino1Evandro A. Nascimento2Carla de M. Martins3Sérgio A. L. de Morais4Roberto Chang5Luís C. S. Cunha6Luís F. Leandro7Carlos H. G. Martins8Mário M. Martins9Claudio V. da Silva10Fabrício C. Machado11Alberto de Oliveira12Laboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilFederal Institute Goiano, Morrinhos, Goiás 75650-000, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilNucleus of Research in Sciences and Technology, Laboratory of Research in Applied Microbiology (LaPeMA), University of Franca, Franca, São Paulo 14404-600, BrazilNucleus of Research in Sciences and Technology, Laboratory of Research in Applied Microbiology (LaPeMA), University of Franca, Franca, São Paulo 14404-600, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilInstitute of Biomedical Sciences, Laboratory of Trypanosomatids, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-902, BrazilInstitute of Biomedical Sciences, Laboratory of Trypanosomatids, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-902, BrazilLaboratory of Natural Products and Chromatography, Chemistry Institute, Federal University of Uberlândia, Uberlândia, Minas Gerais 38408-144, BrazilThe seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound identified. For the stem bark oil obtained during the rainy season, in addition to terpenoids (26.63%), a large amount of fatty acids (46.84%) were identified, in particular palmitic acid (25.40%). Regarding the leaves’ essential oil obtained in the dry season, esters (42.35%) were the main components. The main ester present was (Z)-hex-3-enyl benzoate (10.15%) and the major compound of this oil was (Z)-hex-3-en-1-ol (14.23%). Terpenoids (33.84%), long-chain alkanes (27.04%) and fatty acids (21.72%) were the main components of the essential oil from leaves in the rainy season. Phytol (33.21%), nonacosane (21.95%) and palmitic acid (15.20%) were the major compounds identified. The antimicrobial activity against aerobic and anaerobic oral bacteria was evaluated by the microdilution broth method and cytotoxic activity was carried out with Vero cells. The essential oils from the rainy season showed a better inhibition of the bacterial growth with Minimal Inhibitory Concentrations (MIC) values of 25 or 50 µg·mL−1 for aerobic bacteria, and high selectivity against bacteria was observed. The large amount of fatty acids in rainy season oils may be related to the better inhibitory effects observed.http://www.mdpi.com/1420-3049/19/4/4560Inga laurina (Sw.) Willd.Leguminosaeessential oilantimicrobial activitycytotoxic activity |
| spellingShingle | Fabiana B. Furtado Francisco J. T. de Aquino Evandro A. Nascimento Carla de M. Martins Sérgio A. L. de Morais Roberto Chang Luís C. S. Cunha Luís F. Leandro Carlos H. G. Martins Mário M. Martins Claudio V. da Silva Fabrício C. Machado Alberto de Oliveira Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. Molecules Inga laurina (Sw.) Willd. Leguminosae essential oil antimicrobial activity cytotoxic activity |
| title | Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. |
| title_full | Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. |
| title_fullStr | Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. |
| title_full_unstemmed | Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. |
| title_short | Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd. |
| title_sort | seasonal variation of the chemical composition and antimicrobial and cytotoxic activities of the essential oils from inga laurina sw willd |
| topic | Inga laurina (Sw.) Willd. Leguminosae essential oil antimicrobial activity cytotoxic activity |
| url | http://www.mdpi.com/1420-3049/19/4/4560 |
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