Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved]
Basaloid squamous cell carcinoma (BSCC) is a rare variant of conventional squamous cell carcinoma (SCC) frequently affecting the upper aerodigestive tract. The hypopharynx, tonsil, supraglottic larynx, tongue (base), and head-neck regions are particularly susceptible to BSCC. Clinically, the present...
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| Format: | Article |
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F1000 Research Ltd
2024-03-01
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| Online Access: | https://f1000research.com/articles/12-1008/v3 |
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| author | Samiha Jameel Ahmed Khan Aayushi Pakhale Swati Patil Archana Sonone Alka Hande Madhuri Gawande |
| author_facet | Samiha Jameel Ahmed Khan Aayushi Pakhale Swati Patil Archana Sonone Alka Hande Madhuri Gawande |
| author_sort | Samiha Jameel Ahmed Khan |
| collection | DOAJ |
| description | Basaloid squamous cell carcinoma (BSCC) is a rare variant of conventional squamous cell carcinoma (SCC) frequently affecting the upper aerodigestive tract. The hypopharynx, tonsil, supraglottic larynx, tongue (base), and head-neck regions are particularly susceptible to BSCC. Clinically, the presentation of BSCC and conventional SCC is similar, but BSCC has a poorer prognosis. BSCC is distinguished histopathologically by a dimorphic pattern, a distinctive basal cell component paired with a squamous component. However, its similar features to conventional SCC makes it difficult to diagnose. Therefore, histopathology and immunohistochemistry play a crucial role in diagnosing such tumors. Here we present the case of a 70-year-old male diagnosed with BSCC involving the tongue. |
| first_indexed | 2024-04-24T18:51:12Z |
| format | Article |
| id | doaj.art-e908cebf11ee4927947f02605c8e573f |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-04-24T18:51:12Z |
| publishDate | 2024-03-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-e908cebf11ee4927947f02605c8e573f2024-03-27T01:00:04ZengF1000 Research LtdF1000Research2046-14022024-03-0112164104Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved]Samiha Jameel Ahmed Khan0https://orcid.org/0000-0001-5776-2290Aayushi Pakhale1https://orcid.org/0000-0002-0529-3856Swati Patil2Archana Sonone3https://orcid.org/0000-0001-9225-7919Alka Hande4https://orcid.org/0000-0002-8576-7897Madhuri Gawande5Department of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, IndiaBasaloid squamous cell carcinoma (BSCC) is a rare variant of conventional squamous cell carcinoma (SCC) frequently affecting the upper aerodigestive tract. The hypopharynx, tonsil, supraglottic larynx, tongue (base), and head-neck regions are particularly susceptible to BSCC. Clinically, the presentation of BSCC and conventional SCC is similar, but BSCC has a poorer prognosis. BSCC is distinguished histopathologically by a dimorphic pattern, a distinctive basal cell component paired with a squamous component. However, its similar features to conventional SCC makes it difficult to diagnose. Therefore, histopathology and immunohistochemistry play a crucial role in diagnosing such tumors. Here we present the case of a 70-year-old male diagnosed with BSCC involving the tongue.https://f1000research.com/articles/12-1008/v3Basaloid squamous cell carcinoma dimorphic pattern basaloid cells comedo necrosis eng |
| spellingShingle | Samiha Jameel Ahmed Khan Aayushi Pakhale Swati Patil Archana Sonone Alka Hande Madhuri Gawande Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] F1000Research Basaloid squamous cell carcinoma dimorphic pattern basaloid cells comedo necrosis eng |
| title | Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] |
| title_full | Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] |
| title_fullStr | Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] |
| title_full_unstemmed | Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] |
| title_short | Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report [version 3; peer review: 2 approved] |
| title_sort | case report basaloid squamous cell carcinoma of the tongue a case report version 3 peer review 2 approved |
| topic | Basaloid squamous cell carcinoma dimorphic pattern basaloid cells comedo necrosis eng |
| url | https://f1000research.com/articles/12-1008/v3 |
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