Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico
Introduction: Osteosarcoma is a malignant and primary tumor of the bones. It is characterized by the production of osteoid or immature bone. Radiological images have debeen described that allow identifying the tumor. Objective: To estimate the concordance between conventional radiology and the res...
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| Format: | Article |
| Language: | Spanish |
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Universidad de Cartagena
2013-12-01
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| Series: | Revista Ciencias Biomédicas |
| Subjects: | |
| Online Access: | http://revistacienciasbiomedicas.com/index.php/revciencbiomed/article/view/291/234 |
| _version_ | 1818905615104212992 |
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| author | Duarte-Galván Gustavo Enrique Arrieta-Usta Micaela Ramos Clason Enrique Carlos |
| author_facet | Duarte-Galván Gustavo Enrique Arrieta-Usta Micaela Ramos Clason Enrique Carlos |
| author_sort | Duarte-Galván Gustavo Enrique |
| collection | DOAJ |
| description | Introduction: Osteosarcoma is a malignant and primary tumor of the bones. It is characterized by the production of osteoid or immature bone. Radiological images have debeen
described that allow identifying the tumor.
Objective: To estimate the concordance between conventional radiology and the results
of pathological anatomy in patients with osteosarcoma.
Methods: A study of diagnostic concordance was carried out with data from medical
records, radiological reports and reports of pathological anatomy of 51 patients of both
genders, who were submitted to biopsy of bone tumor due to radiological findings
indicative of malignancy. Data were saved and analyzed in the statistical program
EPI-INFO version 3.5.1. The comparison of proportions for qualitative variables and
comparison of means or medians were done according to the normality criteria for
quantitative variables. The parameters of diagnostic validity of the clinical signs
suggestive of malignancy were determined.
Results: The number of lesions was higher in women than men (53.8% and 46.2%,
respectively). The median of age was 41 years. The most damaged bones were: Femur
49%, tibia 23.5%, humerus and radius 9.8% each one. The most frequent location
was the diaphysis. The most important radiological signs of malignancy were: Sunburst
periosteal reaction and the Codman’s triangle. For single radiology and osteosarcoma,
the sensitivity was 100%, specificity: 92.1%, validity: 94.1%, positive predictive value:
81.2% and negative predictive value: 100%.
Conclusions: The radiology offers good values of concordance for the diagnosis of
osteosarcoma. It is an important method for the approach in the presence of the
suspicion of bone tumor; nevertheless the diagnosis of malignancy must be done by
histopathological study. Rev.cienc.biomed. 2013;4(2):291-2 |
| first_indexed | 2024-12-19T21:26:09Z |
| format | Article |
| id | doaj.art-e90a0f0e90864e17917385887a05478d |
| institution | Directory Open Access Journal |
| issn | 2215-7840 |
| language | Spanish |
| last_indexed | 2024-12-19T21:26:09Z |
| publishDate | 2013-12-01 |
| publisher | Universidad de Cartagena |
| record_format | Article |
| series | Revista Ciencias Biomédicas |
| spelling | doaj.art-e90a0f0e90864e17917385887a05478d2022-12-21T20:05:08ZspaUniversidad de CartagenaRevista Ciencias Biomédicas2215-78402013-12-0142291296Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológicoDuarte-Galván Gustavo Enrique0Arrieta-Usta Micaela1Ramos Clason Enrique Carlos2Médico. Estudiante de posgrado. Radiología. Facultad de Medicina. Universidad de Cartagena. Colombia.Médico. Especialista en Radiología. Docente. Facultad de Medicina. Universidad de Cartagena. Colombia.Médico. Magíster en Salud Pública. Profesor. Departamento de Investigaciones. Facultad de Medicina. Universidad de Cartagena. Colombia.Introduction: Osteosarcoma is a malignant and primary tumor of the bones. It is characterized by the production of osteoid or immature bone. Radiological images have debeen described that allow identifying the tumor. Objective: To estimate the concordance between conventional radiology and the results of pathological anatomy in patients with osteosarcoma. Methods: A study of diagnostic concordance was carried out with data from medical records, radiological reports and reports of pathological anatomy of 51 patients of both genders, who were submitted to biopsy of bone tumor due to radiological findings indicative of malignancy. Data were saved and analyzed in the statistical program EPI-INFO version 3.5.1. The comparison of proportions for qualitative variables and comparison of means or medians were done according to the normality criteria for quantitative variables. The parameters of diagnostic validity of the clinical signs suggestive of malignancy were determined. Results: The number of lesions was higher in women than men (53.8% and 46.2%, respectively). The median of age was 41 years. The most damaged bones were: Femur 49%, tibia 23.5%, humerus and radius 9.8% each one. The most frequent location was the diaphysis. The most important radiological signs of malignancy were: Sunburst periosteal reaction and the Codman’s triangle. For single radiology and osteosarcoma, the sensitivity was 100%, specificity: 92.1%, validity: 94.1%, positive predictive value: 81.2% and negative predictive value: 100%. Conclusions: The radiology offers good values of concordance for the diagnosis of osteosarcoma. It is an important method for the approach in the presence of the suspicion of bone tumor; nevertheless the diagnosis of malignancy must be done by histopathological study. Rev.cienc.biomed. 2013;4(2):291-2http://revistacienciasbiomedicas.com/index.php/revciencbiomed/article/view/291/234Radiology; Osteosarcoma; Bone Neoplasms. |
| spellingShingle | Duarte-Galván Gustavo Enrique Arrieta-Usta Micaela Ramos Clason Enrique Carlos Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico Revista Ciencias Biomédicas Radiology; Osteosarcoma; Bone Neoplasms. |
| title | Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico |
| title_full | Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico |
| title_fullStr | Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico |
| title_full_unstemmed | Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico |
| title_short | Concordancia del diagnóstico de osteosarcoma por radiología convencional vs diagnóstico histopatológico |
| title_sort | concordancia del diagnostico de osteosarcoma por radiologia convencional vs diagnostico histopatologico |
| topic | Radiology; Osteosarcoma; Bone Neoplasms. |
| url | http://revistacienciasbiomedicas.com/index.php/revciencbiomed/article/view/291/234 |
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