Seleno-Analogs of Scaffolds Resembling Natural Products a Novel Warhead toward Dual Compounds
Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated well-established preventive effects against both diseases. In this study, a total...
Main Authors: | Nora Astrain-Redin, Irene Talavera, Esther Moreno, María J. Ramírez, Nuria Martínez-Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/12/1/139 |
Similar Items
-
Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors
by: Nora Astrain-Redin, et al.
Published: (2023-12-01) -
First Generation of Antioxidant Precursors for Bioisosteric Se-NSAIDs: Design, Synthesis, and In Vitro and In Vivo Anticancer Evaluation
by: Sandra Ramos-Inza, et al.
Published: (2023-08-01) -
Novel Acylselenourea Derivatives: Dual Molecules with Anticancer and Radical Scavenging Activity
by: Nora Astrain-Redin, et al.
Published: (2023-06-01) -
Synthesis of benzothiophene and indole derivatives through metal-free propargyl–allene rearrangement and allyl migration
by: Jinzhong Yao, et al.
Published: (2017-09-01) -
Photochemistry of Hydrocarbon Radicals
by: Ingo Fischer
Published: (2000-03-01)