Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study
Abstract Background and Aims Hyperuricemia constitutes a major public health issue due to its implication in many chronic diseases and metabolic syndromes. We propose to study the prevalence and associated factors of hyperuricemia to diagnose asymptomatic patients and make prognoses on the state of...
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| Format: | Article |
| Language: | English |
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Wiley
2024-02-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.1891 |
| _version_ | 1797221180566929408 |
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| author | Romaric De Manfouo Tuono Aude Bernie Famessi Samou Marius Tchoumke Mbiandjeu Pascal Blaise A Koul Well A Well Pascal Dieudonne Djamen Chuisseu |
| author_facet | Romaric De Manfouo Tuono Aude Bernie Famessi Samou Marius Tchoumke Mbiandjeu Pascal Blaise A Koul Well A Well Pascal Dieudonne Djamen Chuisseu |
| author_sort | Romaric De Manfouo Tuono |
| collection | DOAJ |
| description | Abstract Background and Aims Hyperuricemia constitutes a major public health issue due to its implication in many chronic diseases and metabolic syndromes. We propose to study the prevalence and associated factors of hyperuricemia to diagnose asymptomatic patients and make prognoses on the state of health of the patients. Methods An analytic cross‐sectional study has been carried out at the Bafoussam Regional Hospital and the Biochemistry laboratory of the Université des Montagnes over 2 months. Sociodemographic and anthropometric characteristic was obtained; a blood sample was collected from the chosen patients and a biochemical test (uric acid, creatinine, urea, total cholesterol, high density lipoproteins cholesterol, triglyceride) was analyzed by spectrophotometric method. Statistical tests were carried out using SPSS statistical software. Logistic regression analyses identified factors associated with variables of interest. The significance was measured by a p < 0.05 with a confidential level of 95%. Results The patient population was made up of 100 patients. The sex ratio was 1.22 in favor of men. The prevalence of hyperuricemia in our study was 28.0% with 31.1% in women and 27.3% in men. The mean average of uric acid in the hyperuricemia population was 7.50 ± 1.24 mg/L and the normal uricemia population was 4.69 ± 1.49 mg/L (p < 0.0001). The mean average triglyceride in the hyperuricemia population was 143 ± 14 and 117.55 ± 55.52 mg/dL in normal uricemia with p = 0.046. Age range [35–45] and hypertriglyceridemia have been associated with hyperuricemia with respectively (odds ratio [OR] = 4.07, p < 0.015) confidence interval, CI: [0.89: 97.0]) and ([OR = 2.50, p < 0.046] CI: [1.01: 6.09]). Conclusion The prevalence of hyperuricemia was relatively high and has been associated with metabolic disorders in the population. It is necessary to focus on early diagnoses, treatment, and early intervention in view to prevent chronic diseases associated with hyperuricemia. |
| first_indexed | 2024-03-07T19:01:53Z |
| format | Article |
| id | doaj.art-e912190f31db4e9cb2e5adc2259955e0 |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-04-24T13:01:20Z |
| publishDate | 2024-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-e912190f31db4e9cb2e5adc2259955e02024-04-05T11:41:32ZengWileyHealth Science Reports2398-88352024-02-0172n/an/a10.1002/hsr2.1891Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional studyRomaric De Manfouo Tuono0Aude Bernie Famessi Samou1Marius Tchoumke Mbiandjeu2Pascal Blaise A Koul Well A Well3Pascal Dieudonne Djamen Chuisseu4Higher Institute of Health Sciences Université des Montagnes Bangangté CameroonHigher Institute of Health Sciences Université des Montagnes Bangangté CameroonHigher Institute of Health Sciences Université des Montagnes Bangangté CameroonHigher Institute of Health Sciences Université des Montagnes Bangangté CameroonHigher Institute of Health Sciences Université des Montagnes Bangangté CameroonAbstract Background and Aims Hyperuricemia constitutes a major public health issue due to its implication in many chronic diseases and metabolic syndromes. We propose to study the prevalence and associated factors of hyperuricemia to diagnose asymptomatic patients and make prognoses on the state of health of the patients. Methods An analytic cross‐sectional study has been carried out at the Bafoussam Regional Hospital and the Biochemistry laboratory of the Université des Montagnes over 2 months. Sociodemographic and anthropometric characteristic was obtained; a blood sample was collected from the chosen patients and a biochemical test (uric acid, creatinine, urea, total cholesterol, high density lipoproteins cholesterol, triglyceride) was analyzed by spectrophotometric method. Statistical tests were carried out using SPSS statistical software. Logistic regression analyses identified factors associated with variables of interest. The significance was measured by a p < 0.05 with a confidential level of 95%. Results The patient population was made up of 100 patients. The sex ratio was 1.22 in favor of men. The prevalence of hyperuricemia in our study was 28.0% with 31.1% in women and 27.3% in men. The mean average of uric acid in the hyperuricemia population was 7.50 ± 1.24 mg/L and the normal uricemia population was 4.69 ± 1.49 mg/L (p < 0.0001). The mean average triglyceride in the hyperuricemia population was 143 ± 14 and 117.55 ± 55.52 mg/dL in normal uricemia with p = 0.046. Age range [35–45] and hypertriglyceridemia have been associated with hyperuricemia with respectively (odds ratio [OR] = 4.07, p < 0.015) confidence interval, CI: [0.89: 97.0]) and ([OR = 2.50, p < 0.046] CI: [1.01: 6.09]). Conclusion The prevalence of hyperuricemia was relatively high and has been associated with metabolic disorders in the population. It is necessary to focus on early diagnoses, treatment, and early intervention in view to prevent chronic diseases associated with hyperuricemia.https://doi.org/10.1002/hsr2.1891associated factorshyperuricemiauric acid |
| spellingShingle | Romaric De Manfouo Tuono Aude Bernie Famessi Samou Marius Tchoumke Mbiandjeu Pascal Blaise A Koul Well A Well Pascal Dieudonne Djamen Chuisseu Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study Health Science Reports associated factors hyperuricemia uric acid |
| title | Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study |
| title_full | Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study |
| title_fullStr | Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study |
| title_full_unstemmed | Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study |
| title_short | Hyperuricemia and associated factors: The case of outpatients at the Bafoussam Regional Hospital‐ Cameroon, an analytical cross‐sectional study |
| title_sort | hyperuricemia and associated factors the case of outpatients at the bafoussam regional hospital cameroon an analytical cross sectional study |
| topic | associated factors hyperuricemia uric acid |
| url | https://doi.org/10.1002/hsr2.1891 |
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