Fibrillar Collagen Type I Participates in the Survival and Aggregation of Primary Hepatocytes Cultured on Soft Hydrogels

Fibrillar Collagen Type I Participates in the Survival and Aggregation of Primary Hepatocytes Cultured on Soft Hydrogels

Liver is an essential organ that carries out multiple functions such as glycogen storage, the synthesis of plasma proteins, and the detoxification of xenobiotics. Hepatocytes are the parenchyma that sustain almost all the functions supported by this organ. Hepatocytes and non-parenchymal cells respo...

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Bibliographic Details
Main Authors: Nathalia Serna-Márquez, Adriana Rodríguez-Hernández, Marisol Ayala-Reyes, Lorena Omega Martínez-Hernández, Miguel Ángel Peña-Rico, Jorge Carretero-Ortega, Mathieu Hautefeuille, Genaro Vázquez-Victorio
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomimetics
Subjects:
primary hepatocytes
polyacrylamide hydrogels
stiffness
collagen
basement membrane
actin cytoskeleton
Online Access:https://www.mdpi.com/2313-7673/5/2/30

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