The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCO<sub>3</sub><sup>−</sup> by the Porcine Colon

The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCO<sub>3</sub><sup>−</sup> by the Porcine Colon

A therapeutic potential of the TRPA1 channel agonist cinnamaldehyde for use in inflammatory bowel disease is emerging, but the mechanisms are unclear. Semi-quantitative qPCR of various parts of the porcine gastrointestinal tract showed that mRNA for TRPA1 was highest in the colonic mucosa. In Ussing...

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Bibliographic Details
Main Authors:	David Manneck, Gisela Manz, Hannah-Sophie Braun, Julia Rosendahl, Friederike Stumpff
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	International Journal of Molecular Sciences
Subjects:	cinnamaldehyde colon colonic buffering epithelial transport essential oils intestine
Online Access:	https://www.mdpi.com/1422-0067/22/10/5198

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