Case series of intravenous ketamine infusion in patients with suicidal thought
Suicide is the fourth leading cause of death. The annual global prevalence of suicidal ideas in adult population is 2%. Antidepressants are considered to be the first line of treatment for depression but the maximum response is noted only after 4–6 weeks. However, adding ketamine has shown very rapi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Industrial Psychiatry Journal |
| Subjects: | |
| Online Access: | http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2023;volume=32;issue=2;spage=437;epage=440;aulast=Sharma |
| _version_ | 1797245373141483520 |
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| author | Pankaj Sharma Amresh Dubey Deven Gajbhiye Arti Sharma Akhilesh Kant |
| author_facet | Pankaj Sharma Amresh Dubey Deven Gajbhiye Arti Sharma Akhilesh Kant |
| author_sort | Pankaj Sharma |
| collection | DOAJ |
| description | Suicide is the fourth leading cause of death. The annual global prevalence of suicidal ideas in adult population is 2%. Antidepressants are considered to be the first line of treatment for depression but the maximum response is noted only after 4–6 weeks. However, adding ketamine has shown very rapid response (within hours) and high remission rates in patients with depression. Here, we present case series of five depressive patients on treatment with antidepressants having suicidal thoughts. All participants received ketamine infusion 0.5 mg/kg over 45 min at a weekly interval as add-on treatment to ongoing treatment. The responses were assessed by using Montgomery Åsberg Depression Rating Scale psychometric tool. The finding indicates that ketamine infusion had a rapid, antisuicidal effect and is safe when used for a short period. |
| first_indexed | 2024-04-24T19:25:52Z |
| format | Article |
| id | doaj.art-e91a6e08c4c84674a0aad82659cadb89 |
| institution | Directory Open Access Journal |
| issn | 0972-6748 0976-2795 |
| language | English |
| last_indexed | 2024-04-24T19:25:52Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Industrial Psychiatry Journal |
| spelling | doaj.art-e91a6e08c4c84674a0aad82659cadb892024-03-25T15:40:37ZengWolters Kluwer Medknow PublicationsIndustrial Psychiatry Journal0972-67480976-27952023-01-0132243744010.4103/ipj.ipj_19_23Case series of intravenous ketamine infusion in patients with suicidal thoughtPankaj SharmaAmresh DubeyDeven GajbhiyeArti SharmaAkhilesh KantSuicide is the fourth leading cause of death. The annual global prevalence of suicidal ideas in adult population is 2%. Antidepressants are considered to be the first line of treatment for depression but the maximum response is noted only after 4–6 weeks. However, adding ketamine has shown very rapid response (within hours) and high remission rates in patients with depression. Here, we present case series of five depressive patients on treatment with antidepressants having suicidal thoughts. All participants received ketamine infusion 0.5 mg/kg over 45 min at a weekly interval as add-on treatment to ongoing treatment. The responses were assessed by using Montgomery Åsberg Depression Rating Scale psychometric tool. The finding indicates that ketamine infusion had a rapid, antisuicidal effect and is safe when used for a short period.http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2023;volume=32;issue=2;spage=437;epage=440;aulast=Sharmaketamine infusionketamine infusion in depressionsuicidal thought |
| spellingShingle | Pankaj Sharma Amresh Dubey Deven Gajbhiye Arti Sharma Akhilesh Kant Case series of intravenous ketamine infusion in patients with suicidal thought Industrial Psychiatry Journal ketamine infusion ketamine infusion in depression suicidal thought |
| title | Case series of intravenous ketamine infusion in patients with suicidal thought |
| title_full | Case series of intravenous ketamine infusion in patients with suicidal thought |
| title_fullStr | Case series of intravenous ketamine infusion in patients with suicidal thought |
| title_full_unstemmed | Case series of intravenous ketamine infusion in patients with suicidal thought |
| title_short | Case series of intravenous ketamine infusion in patients with suicidal thought |
| title_sort | case series of intravenous ketamine infusion in patients with suicidal thought |
| topic | ketamine infusion ketamine infusion in depression suicidal thought |
| url | http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2023;volume=32;issue=2;spage=437;epage=440;aulast=Sharma |
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