Benzo[<i>f</i>]indole-4,9-dione Derivatives Effectively Inhibit the Growth of Triple-Negative Breast Cancer

Benzo[<i>f</i>]indole-4,9-dione Derivatives Effectively Inhibit the Growth of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor clinical outcome, and currently no effective targeted therapies are available. Indole compounds have been shown to have potential antitumor activity against various cancer cells. In the present study, we found that new four...

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Bibliographic Details
Main Authors: Fabiana Sélos Guerra, Flaviana Rodrigues Fintelman Dias, Anna Claudia Cunha, Patricia Dias Fernandes
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
benzo[<i>f</i>]indole-4,9-dione
cancer
breast cancer
triple-negative breast cancer
apoptosis
cell cycle
Online Access:https://www.mdpi.com/1420-3049/26/15/4414

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