Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres

Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres

Purpose To evaluate a new chronic glaucoma model produced by intracameral injection of dexamethasone-loaded poly lactic-co-glycolic acid microspheres (Dex-PLGA-Ms) over six months. Methods Healthy rats received two injections (at baseline and Week 4) of Dex-PLGA-Ms into the anterior chamber of the r...

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Bibliographic Details
Main Authors: MJ Rodrigo, D Garcia-Herranz, A Aragón-Navas, M Subias, T Martinez-Rincón, S Mendez-Martínez, MJ Cardiel, J García-Feijoo, J Ruberte, R Herrero-Vanrell, L Pablo, E Garcia-Martin, I Bravo-Osuna
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
glaucoma
animal model
plga microspheres
neurodegeneration
dexamethasone
Online Access:http://dx.doi.org/10.1080/10717544.2021.1998245

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