Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis
Atopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2022-11-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/3033 |
| _version_ | 1797694974646550528 |
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| author | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova |
| author_facet | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | Atopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD requires constant care and use of medications with active regenerative properties. The inclusion of anti-inflammatory components in the composition of modern emollients (zinc sulfate and sucralfate) is crucial for restoring the microbiome and immune mechanisms controlling the skin. This article presents data on pathogenetic applicability and clinical efficacy of emollients with anti-inflammatory compounds in patients with AD. |
| first_indexed | 2024-03-12T03:05:36Z |
| format | Article |
| id | doaj.art-e9236e53a6a94dd58200d0e8da0b6709 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T03:05:36Z |
| publishDate | 2022-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-e9236e53a6a94dd58200d0e8da0b67092023-09-03T14:32:59Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352022-11-0121537838210.15690/vsp.v21i5.24572058Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic DermatitisNikolay N. Murashkin0Roza Y. Nezhvedilova1Dmitri V. Fedorov2Roman V. Epishev3Roman A. Ivanov4Alexander I. Materikin5Leonid A. Opryatin6Alena A. Savelova7Lyudmila L. Rusakova8НМИЦ здоровья детей; Первый МГМУ им. И.М. Сеченова (Сеченовский Университет); ЦГМА Управления делами Президента РФНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейНМИЦ здоровья детейAtopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD requires constant care and use of medications with active regenerative properties. The inclusion of anti-inflammatory components in the composition of modern emollients (zinc sulfate and sucralfate) is crucial for restoring the microbiome and immune mechanisms controlling the skin. This article presents data on pathogenetic applicability and clinical efficacy of emollients with anti-inflammatory compounds in patients with AD.https://vsp.spr-journal.ru/jour/article/view/3033детиатопический дерматитатопический маршэпидермальный барьерstaphylococcus aureusроговой слойтранскутанная сенсибилизация |
| spellingShingle | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis Вопросы современной педиатрии дети атопический дерматит атопический марш эпидермальный барьер staphylococcus aureus роговой слой транскутанная сенсибилизация |
| title | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_full | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_fullStr | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_full_unstemmed | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_short | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_sort | scientific and practical innovations in restoring skin barrier properties in children with atopic dermatitis |
| topic | дети атопический дерматит атопический марш эпидермальный барьер staphylococcus aureus роговой слой транскутанная сенсибилизация |
| url | https://vsp.spr-journal.ru/jour/article/view/3033 |
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