3,4-Dihydro-2H-1,3-benzoxazines and their oxo-derivatives - Chemistry and bioactivities

3,4-Dihydro-2H-1,3-benzoxazines derivatives are a significant class of heterocycles with particular awareness due to their remarkable biological activities in humans, plants and animals, and also their natural occurrence. Alteration in the benzoxazine skeleton and their comparative chemical simplici...

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Bibliographic Details
Main Author: Sharaf El-Din Nabaweya Abd El-Salam
Format: Article
Language:English
Published: Serbian Chemical Society 2021-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2021/0352-51391900001S.pdf
Description
Summary:3,4-Dihydro-2H-1,3-benzoxazines derivatives are a significant class of heterocycles with particular awareness due to their remarkable biological activities in humans, plants and animals, and also their natural occurrence. Alteration in the benzoxazine skeleton and their comparative chemical simplicity and accessibility, make these compounds suitable sources of other bioactive compounds, resulting in the discovery of a wide set of these compounds that have broad biological activity, such as antifungal, antibacterial, anti-HIV, anticancer, anticonvulsant, anti-inflammatory, etc. Subsequently, this review gives herein a brief overview of the chemistry and bioactivities of derivatives of 3,4-dihydro-2H-1,3-benzoxazine monomers and their oxo-derivatives.
ISSN:0352-5139
1820-7421