Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a worldwide challenge; regarding the lack of an effective and efficient drug. It seems that the vaccine is the only modality to save the world from this pandemic. Objectives: This study was conducted to assess the...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2023-06-01
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| Series: | Journal of Nephropharmacology |
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| Online Access: | https://jnephropharmacology.com/PDF/npj-12-e10591.pdf |
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| author | Razieh Mousapour Mostafa Assarroudi Yaser Khanchemehr Masoomeh Mehrbarjou Golmis Abdolmohammadi Farshad Gharebakhshi Erfan Ghanbarzadeh Hussein Soleimantabar |
| author_facet | Razieh Mousapour Mostafa Assarroudi Yaser Khanchemehr Masoomeh Mehrbarjou Golmis Abdolmohammadi Farshad Gharebakhshi Erfan Ghanbarzadeh Hussein Soleimantabar |
| author_sort | Razieh Mousapour |
| collection | DOAJ |
| description | Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a worldwide challenge; regarding the lack of an effective and efficient drug. It seems that the vaccine is the only modality to save the world from this pandemic. Objectives: This study was conducted to assess the effect of vaccination on preventing pulmonary involvement and the disease severity of COVID-19 patients. Patients and Methods: This descriptive-analytical study was conducted on 247 people with coronavirus disease 2019 infection. Demographic characteristics and vaccination status information were collected. Patients’ lung computed tomography scan findings were scored based on the pulmonary involvement percentage, and then according to this score, they were graded into severe, moderate, mild, and without lung involvement. The association between pulmonary involvement and vaccination status were evaluated by Fisher’s exact test and logistic regression. Results: Most participants were male, with a mean age of 53.74 ± 10.96 years. Most people (42.9%) were partial-vaccinated. Lungs in 53.3% were with lung involvement and in 46.6% were without. The correlation between pulmonary involvement and vaccination was significant (P<0.001). Conclusion: Vaccination is an effective and efficient method in preventing coronavirus disease 2019 severity. |
| first_indexed | 2024-03-11T22:29:20Z |
| format | Article |
| id | doaj.art-e92667c9e8b84cc78633bf9c2af73ebb |
| institution | Directory Open Access Journal |
| issn | 2345-4202 |
| language | English |
| last_indexed | 2024-03-11T22:29:20Z |
| publishDate | 2023-06-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropharmacology |
| spelling | doaj.art-e92667c9e8b84cc78633bf9c2af73ebb2023-09-23T11:55:53ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropharmacology2345-42022023-06-01122e10591e1059110.34172/npj.2023.10591npj-10591Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severityRazieh Mousapour0Mostafa Assarroudi1Yaser Khanchemehr2Masoomeh Mehrbarjou3Golmis Abdolmohammadi4Farshad Gharebakhshi5Erfan Ghanbarzadeh6Hussein Soleimantabar7Department of Radiology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Nursing, Torbat Jam Faculty of Medical Sciences, Torbat Jam, IranDepartment of Nursing, Faculty of Nursing & Midwifery, Hormozgan University of Medical Sciences, Bandar Abbas, IranDepartment of Radiology, School of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine Army University of Medical Sciences (AJA University of Medical Sciences), Tehran, IranDepartment of Radiology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranStudent Research Committee, Guilan University of Medical Sciences, Rasht, Guilan, IranDepartment of Radiology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranIntroduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a worldwide challenge; regarding the lack of an effective and efficient drug. It seems that the vaccine is the only modality to save the world from this pandemic. Objectives: This study was conducted to assess the effect of vaccination on preventing pulmonary involvement and the disease severity of COVID-19 patients. Patients and Methods: This descriptive-analytical study was conducted on 247 people with coronavirus disease 2019 infection. Demographic characteristics and vaccination status information were collected. Patients’ lung computed tomography scan findings were scored based on the pulmonary involvement percentage, and then according to this score, they were graded into severe, moderate, mild, and without lung involvement. The association between pulmonary involvement and vaccination status were evaluated by Fisher’s exact test and logistic regression. Results: Most participants were male, with a mean age of 53.74 ± 10.96 years. Most people (42.9%) were partial-vaccinated. Lungs in 53.3% were with lung involvement and in 46.6% were without. The correlation between pulmonary involvement and vaccination was significant (P<0.001). Conclusion: Vaccination is an effective and efficient method in preventing coronavirus disease 2019 severity.https://jnephropharmacology.com/PDF/npj-12-e10591.pdfcovid-19sars-cov-2vaccinationlung involvementpulmonary involvement |
| spellingShingle | Razieh Mousapour Mostafa Assarroudi Yaser Khanchemehr Masoomeh Mehrbarjou Golmis Abdolmohammadi Farshad Gharebakhshi Erfan Ghanbarzadeh Hussein Soleimantabar Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity Journal of Nephropharmacology covid-19 sars-cov-2 vaccination lung involvement pulmonary involvement |
| title | Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| title_full | Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| title_fullStr | Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| title_full_unstemmed | Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| title_short | Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| title_sort | immunity due to covid 19 vaccination and its correlation with lung involvement severity as an indicator of disease severity |
| topic | covid-19 sars-cov-2 vaccination lung involvement pulmonary involvement |
| url | https://jnephropharmacology.com/PDF/npj-12-e10591.pdf |
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