Unique amplification of BCR-ABL1 gene fusion in a case of T-cell acute lymphoblastic leukemia

Unique amplification of BCR-ABL1 gene fusion in a case of T-cell acute lymphoblastic leukemia

Abstract Background ABL1 gene translocations can be seen in precursor T-acute lymphoblastic leukemia (T-ALL). The typical translocation partner is the NUP214 gene. BCR-ABL translocations are relatively rare in this entity. Furthermore, while there have been unique patterns of amplification noted amo...

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Bibliographic Details
Main Authors: Rima Koka, Najeebah A. Bade, Edward A. Sausville, Yi Ning, Ying Zou
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Molecular Cytogenetics
Subjects:
T-lymphoblastic leukemia
BCR/ABL
Gene amplification
Isodicentric chromosome 22
Derivative chromosome 9
Online Access:http://link.springer.com/article/10.1186/s13039-017-0340-6

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