The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia
Background: Hypotension is one of the most common complications after spinal anesthesia for cesarean delivery. Normally, preloading with fluids, especially crystalloids, is used to prevention of hypotension. Methods: In the present randomized clinical trial study, 120 parturients presenting for elec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Advanced Biomedical Research |
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| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=115;epage=115;aulast=Saghafinia |
| _version_ | 1819065675042258944 |
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| author | Masoud Saghafinia Alireza Jalali Mahnaz Eskandari Nahid Eskandari Marzieh Lak |
| author_facet | Masoud Saghafinia Alireza Jalali Mahnaz Eskandari Nahid Eskandari Marzieh Lak |
| author_sort | Masoud Saghafinia |
| collection | DOAJ |
| description | Background: Hypotension is one of the most common complications after spinal anesthesia for cesarean delivery. Normally, preloading with fluids, especially crystalloids, is used to prevention of hypotension. Methods: In the present randomized clinical trial study, 120 parturients presenting for elective cesarean section with the American Society of Anesthesiologists Class I and II received either 15 cc normal saline or 7 cc/kg hydroxyethyl starch 6% (Voluven) fluid. Information regarding to systolic, diastolic, mean arterial pressure, and heart rate, incidence of hypotension, adverse effects, the total dose of atropine, and ephedrine were recorded in before and 3, 6, 9, 15, and 20 min after spinal anesthesia. Furthermore, Apgar score of newborn at the 1st and 5th min after birth was recorded. Results: There was no significant difference in mean arterial pressure at different stages such as: Exactly after spinal and 3, 6, 15, and 20 min after spinal anesthesia between two groups (P > 0.05). Total dose of ephedrine and atropine were similar between groups (P > 0.05), respectively. There was no significant difference in Apgar score at the 1st and 5th min after birth between two groups. There were not any adverse effects of drugs in two groups. Conclusions: The results of this study show that hydroxyethyl starch 6% compared to normal saline are similar to prevent hypotension during spinal anesthesia for cesarean delivery. |
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| format | Article |
| id | doaj.art-e92bd812b4174c59a9d285d469de40a1 |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-12-21T15:50:14Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-e92bd812b4174c59a9d285d469de40a12022-12-21T18:58:15ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752017-01-016111511510.4103/abr.abr_151_16The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal AnesthesiaMasoud SaghafiniaAlireza JalaliMahnaz EskandariNahid EskandariMarzieh LakBackground: Hypotension is one of the most common complications after spinal anesthesia for cesarean delivery. Normally, preloading with fluids, especially crystalloids, is used to prevention of hypotension. Methods: In the present randomized clinical trial study, 120 parturients presenting for elective cesarean section with the American Society of Anesthesiologists Class I and II received either 15 cc normal saline or 7 cc/kg hydroxyethyl starch 6% (Voluven) fluid. Information regarding to systolic, diastolic, mean arterial pressure, and heart rate, incidence of hypotension, adverse effects, the total dose of atropine, and ephedrine were recorded in before and 3, 6, 9, 15, and 20 min after spinal anesthesia. Furthermore, Apgar score of newborn at the 1st and 5th min after birth was recorded. Results: There was no significant difference in mean arterial pressure at different stages such as: Exactly after spinal and 3, 6, 15, and 20 min after spinal anesthesia between two groups (P > 0.05). Total dose of ephedrine and atropine were similar between groups (P > 0.05), respectively. There was no significant difference in Apgar score at the 1st and 5th min after birth between two groups. There were not any adverse effects of drugs in two groups. Conclusions: The results of this study show that hydroxyethyl starch 6% compared to normal saline are similar to prevent hypotension during spinal anesthesia for cesarean delivery.http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=115;epage=115;aulast=SaghafiniaCesarean sectioncolloidcrystalloidhydroxyl ethyl starchhypotensionVoluven |
| spellingShingle | Masoud Saghafinia Alireza Jalali Mahnaz Eskandari Nahid Eskandari Marzieh Lak The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia Advanced Biomedical Research Cesarean section colloid crystalloid hydroxyl ethyl starch hypotension Voluven |
| title | The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia |
| title_full | The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia |
| title_fullStr | The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia |
| title_full_unstemmed | The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia |
| title_short | The Effects of Hydroxyethyl Starch 6% and Crystalloid on Volume Preloading Changes following Spinal Anesthesia |
| title_sort | effects of hydroxyethyl starch 6 and crystalloid on volume preloading changes following spinal anesthesia |
| topic | Cesarean section colloid crystalloid hydroxyl ethyl starch hypotension Voluven |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=115;epage=115;aulast=Saghafinia |
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