The role of YAP/TAZ activity in cancer metabolic reprogramming

The role of YAP/TAZ activity in cancer metabolic reprogramming

Abstract In contrast to normal cells, which use the aerobic oxidation of glucose as their main energy production method, cancer cells prefer to use anaerobic glycolysis to maintain their growth and survival, even under normoxic conditions. Such tumor cell metabolic reprogramming is regulated by fact...

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Bibliographic Details
Main Authors: Xiaodong Zhang, Haiying Zhao, Yan Li, Di Xia, Liang Yang, Yingbo Ma, Hangyu Li
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Molecular Cancer
Subjects:
YAP/TAZ
Metabolic reprograming
Glycolysis
Gluconeogenesis
Fatty acids
Mevalonate
Online Access:http://link.springer.com/article/10.1186/s12943-018-0882-1

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http://link.springer.com/article/10.1186/s12943-018-0882-1

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