Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines
Objectives. Marijuana is the most commonly used illicit drug during pregnancy. Due to high lipophilicity, cannabinoids can easily penetrate physiological barriers like the human placenta and jeopardize the developing fetus. We evaluated the impact of cannabidiol (CBD), a major non-psychoactive canna...
Main Authors: | Valeria Feinshtein, Offer Erez, Zvi Ben-Zvi, Noam Erez, Tamar Eshkoli, Boaz Sheizaf, Eyal Sheiner, Mahmud Huleihel, Gershon Holcberg |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-09-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/153.pdf |
Similar Items
-
Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner
by: Sereen K. Nashif, et al.
Published: (2023-05-01) -
ZBED1 Regulates Genes Important for Multiple Biological Processes of the Placenta
by: Simone Johansen, et al.
Published: (2022-01-01) -
Differences and Interactions in Placental Manganese and Iron Transfer across an In Vitro Model of Human Villous Trophoblasts
by: Vivien Michaelis, et al.
Published: (2022-03-01) -
Chicken xenobiotic receptor upregulates the BCRP/ABCG2 transporter
by: Ziyong Xu, et al.
Published: (2023-01-01) -
Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy
by: Péter Szatmári, et al.
Published: (2023-08-01)