Advances in the roles of ATF4 in osteoporosis

Advances in the roles of ATF4 in osteoporosis

Osteoporosis (OP) is characterized by reduced bone mass, decreased strength, and enhanced bone fragility fracture risk. Activating transcription factor 4 (ATF4) plays a role in cell differentiation, proliferation, apoptosis, redox balance, amino acid uptake, and glycolipid metabolism. ATF4 induces t...

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Bibliographic Details
Main Authors:	Yaosheng Xiao, Xunlu Xie, Zhixi Chen, Guoqiang Yin, Weihao Kong, Jianguo Zhou
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	ATF4 Osteoporosis Bone remodeling Osteogenic differentiation Osteoblast Osteoclast
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223016621

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