Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis
Objectives: Subacute sclerosing panencephalitis (SSPE) is rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection with measles virus. No cure for SSPE exists, but the condition can be managed by medication if treatment is started at a...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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Series: | Annals of Indian Academy of Neurology |
Subjects: | |
Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=2;spage=275;epage=276;aulast=Das |
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author | Biplab Das Manoj Kumar Goyal Manish Modi Sahil Mehta Sudheer Chakravarthi Vivek Lal Sameer Vyas |
author_facet | Biplab Das Manoj Kumar Goyal Manish Modi Sahil Mehta Sudheer Chakravarthi Vivek Lal Sameer Vyas |
author_sort | Biplab Das |
collection | DOAJ |
description | Objectives: Subacute sclerosing panencephalitis (SSPE) is rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection with measles virus. No cure for SSPE exists, but the condition can be managed by medication if treatment is started at an early stage. Methods and Results: Heterogeneity of imaging findings in SSPE is not very uncommon. But pial and gyral enhancements are very rarely noticed. Significant asymmetric onset as well as pial-gyral enhancements is not reported. Herein we present a case of 16 years adolescent of SSPE having remarkable asymmetric pial-gyral enhancements, which were misinterpreted as tubercular infection. Conclusion: Early diagnosis and treatment is encouraging in SSPE, although it is not curable with current therapy. Clinico-radiological and electrophysiological correlation is very important in diagnosis of SSPE, more gravely in patients having atypical image findings as in our index case. |
first_indexed | 2024-12-14T19:44:50Z |
format | Article |
id | doaj.art-e93558dab0f34ee5bf419fe3fbc806a1 |
institution | Directory Open Access Journal |
issn | 0972-2327 1998-3549 |
language | English |
last_indexed | 2024-12-14T19:44:50Z |
publishDate | 2016-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Annals of Indian Academy of Neurology |
spelling | doaj.art-e93558dab0f34ee5bf419fe3fbc806a12022-12-21T22:49:36ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492016-01-0119227527610.4103/0972-2327.173304Atypical magnetic resonance imaging features in subacute sclerosing panencephalitisBiplab DasManoj Kumar GoyalManish ModiSahil MehtaSudheer ChakravarthiVivek LalSameer VyasObjectives: Subacute sclerosing panencephalitis (SSPE) is rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection with measles virus. No cure for SSPE exists, but the condition can be managed by medication if treatment is started at an early stage. Methods and Results: Heterogeneity of imaging findings in SSPE is not very uncommon. But pial and gyral enhancements are very rarely noticed. Significant asymmetric onset as well as pial-gyral enhancements is not reported. Herein we present a case of 16 years adolescent of SSPE having remarkable asymmetric pial-gyral enhancements, which were misinterpreted as tubercular infection. Conclusion: Early diagnosis and treatment is encouraging in SSPE, although it is not curable with current therapy. Clinico-radiological and electrophysiological correlation is very important in diagnosis of SSPE, more gravely in patients having atypical image findings as in our index case.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=2;spage=275;epage=276;aulast=DasEncephalitismeaslesmyoclonic jerkspial and gyral enhancementsubacute sclerosing panencephalitis (SSPE) |
spellingShingle | Biplab Das Manoj Kumar Goyal Manish Modi Sahil Mehta Sudheer Chakravarthi Vivek Lal Sameer Vyas Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis Annals of Indian Academy of Neurology Encephalitis measles myoclonic jerks pial and gyral enhancement subacute sclerosing panencephalitis (SSPE) |
title | Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
title_full | Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
title_fullStr | Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
title_full_unstemmed | Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
title_short | Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
title_sort | atypical magnetic resonance imaging features in subacute sclerosing panencephalitis |
topic | Encephalitis measles myoclonic jerks pial and gyral enhancement subacute sclerosing panencephalitis (SSPE) |
url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=2;spage=275;epage=276;aulast=Das |
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