The physical dimensions of amyloid aggregates control their infective potential as prion particles
Transmissible amyloid particles called prions are associated with infectious prion diseases in mammals and inherited phenotypes in yeast. All amyloid aggregates can give rise to potentially infectious seeds that accelerate their growth. Why some amyloid seeds are highly infectious prion particles wh...
Main Authors: | Ricardo Marchante, David M Beal, Nadejda Koloteva-Levine, Tracey J Purton, Mick F Tuite, Wei-Feng Xue |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/27109 |
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