Adefovir Dipivoxil as a Therapeutic Candidate for Medullary Thyroid Carcinoma: Targeting RET and STAT3 Proto-Oncogenes

Adefovir Dipivoxil as a Therapeutic Candidate for Medullary Thyroid Carcinoma: Targeting RET and STAT3 Proto-Oncogenes

Aberrant gene expression is often linked to the progression of various cancers, making the targeting of oncogene transcriptional activation a potential strategy to control tumor growth and development. The RET proto-oncogene’s gain-of-function mutation is a major cause of medullary thyroid carcinoma...

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Bibliographic Details
Main Authors: Tariq Alqahtani, Vishnu Kumarasamy, Sahar Saleh Alghamdi, Rasha Saad Suliman, Khalid Bin Saleh, Mohammed A. Alrashed, Mohammed Aldhaeefi, Daekyu Sun
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
medullary thyroid carcinoma
adefovir dipivoxil
RET
STAT3
drug design
Egr-1
Online Access:https://www.mdpi.com/2072-6694/15/7/2163

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