Regulation of hepatic glutamine metabolism by miR-122
Objective: It is well established that the liver-specific miR-122, a bona fide tumor suppressor, plays a critical role in lipid homeostasis. However, its role, if any, in amino acid metabolism has not been explored. Since glutamine (Gln) is a critical energy and anaplerotic source for mammalian cell...
Main Authors: | Dipanwita Sengupta, Teresa Cassel, Kun-yu Teng, Mona Aljuhani, Vivek K. Chowdhary, Peng Hu, Xiaoli Zhang, Teresa W.-M. Fan, Kalpana Ghoshal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-04-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877820300053 |
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