Downregulated PITX1 Modulated by MiR-19a-3p Promotes Cell Malignancy and Predicts a Poor Prognosis of Gastric Cancer by Affecting Transcriptionally Activated PDCD5

Downregulated PITX1 Modulated by MiR-19a-3p Promotes Cell Malignancy and Predicts a Poor Prognosis of Gastric Cancer by Affecting Transcriptionally Activated PDCD5

Background/Aims: PITX1 has been identified as a potential tumor-suppressor gene in several malignant tumors. The molecular mechanism underlying PITX1, particularly its function as a transcription factor regulating gene expression during tumorigenesis, is still poorly understood. Methods: The express...

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Bibliographic Details
Main Authors: Fengchang Qiao, Pihai Gong, Yunwei Song, Xiaohui Shen, Xianwei Su, Yiping Li, Huazhang Wu, Zhujiang Zhao, Hong Fan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Pitx1
PDCD5
Cell proliferation
Cell apoptosis
MiR-19a-3p
Online Access:https://www.karger.com/Article/FullText/489590

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