| Summary: | Alzheimer’s disease is an age-dependent neurodegenerative disease. Recently,
different non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs,
and circular RNAs, have been found to contribute to Alzheimer’s disease’s
pathogenesis. Extracellular vehicles could be enriched in ncRNAs and in their
role in mediating intercellular communication. Signatures of extracellular
vesicular ncRNAs have shown them to be a potential biomarker in Alzheimer’s
disease. This perspective discusses the potential role of extracellular vehicle
ncRNAs in Alzheimer’s disease, providing a theoretical basis for extracellular
vesicular ncRNAs in Alzheimer’s disease, from pathogenesis to diagnosis and
treatment.
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