Preprocessing of Heteroscedastic Medical Images

Tissue intensity distributions in medical images can have varying degrees of statistical dispersion, which is referred to as heteroscedasticity. This can influence image contrast and gradients, but can also negatively affect the performance of general-purpose distance metrics. Numerous methods to pr...

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Main Authors: Philip Joris, Wim Develter, Wim Van De Voorde, Paul Suetens, Frederik Maes, Dirk Vandermeulen, Peter Claes
Format: Article
Language:English
Published: IEEE 2018-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8354895/
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author Philip Joris
Wim Develter
Wim Van De Voorde
Paul Suetens
Frederik Maes
Dirk Vandermeulen
Peter Claes
author_facet Philip Joris
Wim Develter
Wim Van De Voorde
Paul Suetens
Frederik Maes
Dirk Vandermeulen
Peter Claes
author_sort Philip Joris
collection DOAJ
description Tissue intensity distributions in medical images can have varying degrees of statistical dispersion, which is referred to as heteroscedasticity. This can influence image contrast and gradients, but can also negatively affect the performance of general-purpose distance metrics. Numerous methods to preprocess heteroscedastic images have already been proposed, though most are application-specific and rely on either manual input or certain heuristics. We therefore propose a more general and data-driven approach that relies on the notion of intensity variance around each specific intensity value, simply referred to as intensityspecific variances. First, we introduce a method for estimating these variances from an image (or a collection of images) directly, which is followed by an illustration of how they can be used to define intensity-specific distance measures. Next, we evaluate the proposed concepts through various applications using both homoand heteroscedastic CT and MR images. Finally, we present results from both qualitative and quantitative analyses that confirm the working of the proposed approaches, and support the presented concepts as valid and effective tools for (pre)processing heteroscedastic medical images.
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spelling doaj.art-e9450b4d06b24da3b8f2c303c5724f542022-12-21T23:44:19ZengIEEEIEEE Access2169-35362018-01-016260472605810.1109/ACCESS.2018.28332868354895Preprocessing of Heteroscedastic Medical ImagesPhilip Joris0https://orcid.org/0000-0001-6848-1259Wim Develter1Wim Van De Voorde2Paul Suetens3Frederik Maes4Dirk Vandermeulen5Peter Claes6Department ESAT-PSI, Medical Imaging Research Center, KU Leuven, Leuven, BelgiumDepartment of Forensic Medicine, University Hospitals UZ Leuven, Leuven, BelgiumDepartment of Forensic Medicine, University Hospitals UZ Leuven, Leuven, BelgiumDepartment ESAT-PSI, Medical Imaging Research Center, KU Leuven, Leuven, BelgiumDepartment ESAT-PSI, Medical Imaging Research Center, KU Leuven, Leuven, BelgiumDepartment ESAT-PSI, Medical Imaging Research Center, KU Leuven, Leuven, BelgiumDepartment ESAT-PSI, Medical Imaging Research Center, KU Leuven, Leuven, BelgiumTissue intensity distributions in medical images can have varying degrees of statistical dispersion, which is referred to as heteroscedasticity. This can influence image contrast and gradients, but can also negatively affect the performance of general-purpose distance metrics. Numerous methods to preprocess heteroscedastic images have already been proposed, though most are application-specific and rely on either manual input or certain heuristics. We therefore propose a more general and data-driven approach that relies on the notion of intensity variance around each specific intensity value, simply referred to as intensityspecific variances. First, we introduce a method for estimating these variances from an image (or a collection of images) directly, which is followed by an illustration of how they can be used to define intensity-specific distance measures. Next, we evaluate the proposed concepts through various applications using both homoand heteroscedastic CT and MR images. Finally, we present results from both qualitative and quantitative analyses that confirm the working of the proposed approaches, and support the presented concepts as valid and effective tools for (pre)processing heteroscedastic medical images.https://ieeexplore.ieee.org/document/8354895/Heteroscedasticheteroscedasticityimage contrastimage enhancementintensity-specific distributions
spellingShingle Philip Joris
Wim Develter
Wim Van De Voorde
Paul Suetens
Frederik Maes
Dirk Vandermeulen
Peter Claes
Preprocessing of Heteroscedastic Medical Images
IEEE Access
Heteroscedastic
heteroscedasticity
image contrast
image enhancement
intensity-specific distributions
title Preprocessing of Heteroscedastic Medical Images
title_full Preprocessing of Heteroscedastic Medical Images
title_fullStr Preprocessing of Heteroscedastic Medical Images
title_full_unstemmed Preprocessing of Heteroscedastic Medical Images
title_short Preprocessing of Heteroscedastic Medical Images
title_sort preprocessing of heteroscedastic medical images
topic Heteroscedastic
heteroscedasticity
image contrast
image enhancement
intensity-specific distributions
url https://ieeexplore.ieee.org/document/8354895/
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