Palmitoylethanolamide (PEA) Inhibits SARS-CoV-2 Entry by Interacting with S Protein and ACE-2 Receptor

Palmitoylethanolamide (PEA) Inhibits SARS-CoV-2 Entry by Interacting with S Protein and ACE-2 Receptor

Lipids play a crucial role in the entry and egress of viruses, regardless of whether they are naked or enveloped. Recent evidence shows that lipid involvement in viral infection goes much further. During replication, many viruses rearrange internal lipid membranes to create niches where they replica...

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Bibliographic Details
Main Authors: Rossella Fonnesu, Venkata Bala Sai Chaitanya Thunuguntla, Ganesh Kumar Veeramachaneni, Jayakumar Singh Bondili, Veronica La Rocca, Carolina Filipponi, Pietro Giorgio Spezia, Maria Sidoti, Erika Plicanti, Paola Quaranta, Giulia Freer, Mauro Pistello, Michael Lee Mathai, Michele Lai
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
SARS-CoV-2
bioactive lipids
nutraceutical
antiviral
spike protein
PEA
Online Access:https://www.mdpi.com/1999-4915/14/5/1080

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