Towards Improved Management of Tuberculous Bloodstream Infections: Pharmacokinetic Considerations with Suggestions for Better Treatment Outcomes

Towards Improved Management of Tuberculous Bloodstream Infections: Pharmacokinetic Considerations with Suggestions for Better Treatment Outcomes

<i>Mycobacterium tuberculosis</i> is the leading cause of sepsis among HIV-infected adults, yet effective treatment remains a challenge. Efficacy of antituberculous drugs is optimized by high Area Under Curve to Minimum Inhibitory Concentration (AUC/MIC) ratios, suggesting that both the...

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Bibliographic Details
Main Authors: Charles Okot Odongo, Lydia Nakiyingi, Clovis Gatete Nkeramihigo, Daniel Seifu, Kuteesa Ronald Bisaso
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antibiotics
Subjects:
tuberculosis
sepsis
treatment
pharmacokinetics
C<sub>max</sub>
AUC
Online Access:https://www.mdpi.com/2079-6382/11/7/895

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