Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study

Abstract Background In an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains con...

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Main Authors: Hong Xu, Jingli Yang, Jinwei Xie, Zeyu Huang, Qiang Huang, Guorui Cao, Fuxing Pei
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-020-03623-5
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author Hong Xu
Jingli Yang
Jinwei Xie
Zeyu Huang
Qiang Huang
Guorui Cao
Fuxing Pei
author_facet Hong Xu
Jingli Yang
Jinwei Xie
Zeyu Huang
Qiang Huang
Guorui Cao
Fuxing Pei
author_sort Hong Xu
collection DOAJ
description Abstract Background In an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains controversial. Therefore, we carried out a study to investigate the effect of tourniquet application in routine primary TKA on transfusion rate and PLOS. Methods We analyzed data from 6325 patients who underwent primary unilateral TKA and divided them into two groups according to whether a tourniquet was applied during the procedure, and a tourniquet was used in 4902 and not used in 1423. The information for transfusion and PLOS was extracted from patients’ electronic health records, and the data were analyzed with logistic and linear regression analyses. Results Following TKA, the transfusion rate and PLOS were 14.52% and 7.72 ± 3.54 days, respectively, in the tourniquet group, and 6.47% and 6.44 ± 3.48 days, respectively, in the no-tourniquet group. After adjusting for the different related variables, tourniquet use was significantly correlated with a higher transfusion rate (risk ratio = 1.888, 95% confidence interval (CI) 1.449–2.461, P < 0.001) and a longer PLOS (partial regression coefficient (B) = 0.923, 95%CI 0.690–1.156, P < 0.001). Conclusions Our findings suggested that tourniquet use in routine primary TKA was related to a higher transfusion rate and a longer PLOS. The impact of tourniquet use on transfusion rate and PLOS should be taken into account in clinical practice.
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spelling doaj.art-e947e3955975495ba83aed8a6e646aee2022-12-21T23:53:47ZengBMCBMC Musculoskeletal Disorders1471-24742020-09-012111810.1186/s12891-020-03623-5Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world studyHong Xu0Jingli Yang1Jinwei Xie2Zeyu Huang3Qiang Huang4Guorui Cao5Fuxing Pei6Department of Orthopaedic surgery and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan UniversityCollege of Earth and Environmental Sciences, School of Public Health, Lanzhou UniversityDepartment of Orthopaedic surgery and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan UniversityDepartment of Orthopaedic surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic surgery, West China Hospital, Sichuan UniversityAbstract Background In an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains controversial. Therefore, we carried out a study to investigate the effect of tourniquet application in routine primary TKA on transfusion rate and PLOS. Methods We analyzed data from 6325 patients who underwent primary unilateral TKA and divided them into two groups according to whether a tourniquet was applied during the procedure, and a tourniquet was used in 4902 and not used in 1423. The information for transfusion and PLOS was extracted from patients’ electronic health records, and the data were analyzed with logistic and linear regression analyses. Results Following TKA, the transfusion rate and PLOS were 14.52% and 7.72 ± 3.54 days, respectively, in the tourniquet group, and 6.47% and 6.44 ± 3.48 days, respectively, in the no-tourniquet group. After adjusting for the different related variables, tourniquet use was significantly correlated with a higher transfusion rate (risk ratio = 1.888, 95% confidence interval (CI) 1.449–2.461, P < 0.001) and a longer PLOS (partial regression coefficient (B) = 0.923, 95%CI 0.690–1.156, P < 0.001). Conclusions Our findings suggested that tourniquet use in routine primary TKA was related to a higher transfusion rate and a longer PLOS. The impact of tourniquet use on transfusion rate and PLOS should be taken into account in clinical practice.http://link.springer.com/article/10.1186/s12891-020-03623-5TourniquetKneeArthroplastyTransfusionLength of stay
spellingShingle Hong Xu
Jingli Yang
Jinwei Xie
Zeyu Huang
Qiang Huang
Guorui Cao
Fuxing Pei
Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
BMC Musculoskeletal Disorders
Tourniquet
Knee
Arthroplasty
Transfusion
Length of stay
title Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
title_full Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
title_fullStr Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
title_full_unstemmed Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
title_short Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study
title_sort tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay a real world study
topic Tourniquet
Knee
Arthroplasty
Transfusion
Length of stay
url http://link.springer.com/article/10.1186/s12891-020-03623-5
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