Functional profiling of live melanoma samples using a novel automated platform.
This proof-of-concept study was designed to determine if functional, pharmacodynamic profiles relevant to targeted therapy could be derived from live human melanoma samples using a novel automated platform.A series of 13 melanoma cell lines was briefly exposed to a BRAF inhibitor (PLX-4720) on a pla...
Main Authors: | Adam Schayowitz, Greg Bertenshaw, Emiko Jeffries, Timothy Schatz, James Cotton, Jessie Villanueva, Meenhard Herlyn, Clemens Krepler, Adina Vultur, Wei Xu, Gordon H Yu, Lynn Schuchter, Douglas P Clark |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3532357?pdf=render |
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