Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study
Background: Atopic dermatitis (AD) is an important issue, significance of which is determined by the incidence increase, chronic, relapsing course of the disease, and poor treatment efficacy.Objective: Our aim was to study clinical efficacy of enterosorbent based on pectin, inulin and fennel extract...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2016-08-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1639 |
| _version_ | 1797702248855240704 |
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| author | Elena I. Danilova Oksana Yu. Trusova Anton N. Roschupkin Zinaida A. Veterkova Ekaterina I. Golovacheva Tatiana N. Ignatova |
| author_facet | Elena I. Danilova Oksana Yu. Trusova Anton N. Roschupkin Zinaida A. Veterkova Ekaterina I. Golovacheva Tatiana N. Ignatova |
| author_sort | Elena I. Danilova |
| collection | DOAJ |
| description | Background: Atopic dermatitis (AD) is an important issue, significance of which is determined by the incidence increase, chronic, relapsing course of the disease, and poor treatment efficacy.Objective: Our aim was to study clinical efficacy of enterosorbent based on pectin, inulin and fennel extract in combined AD treatment in children.Methods: «Case-control» prospective study included children from 3 to 11 years admitted to hospital with moderate AD.Results: 20 patients included in the study took enterosorbent in addition to the basic therapy, 20 patients had only basic therapy. Compared groups were matched by sex, age, and AD severity by SCORAD scale. Cutaneous AD manifestations in the main group were arrested average over the period of 3.4 ± 1.2 days, in the control group — of 4.7 ± 1.5 days (p < 0.001), skin itch — of 4.0 ± 0.9 and 6.8 ± 1.4 days (p < 0.001), skin dryness — of 9.8 ± 1.1 and 12.3 ± 1.6 days, respectively (р < 0.001).Conclusion: Adding enterosorbent containing pectin, inulin and fennel extract to the basic therapy of moderate AD makes it easier to arrest the clinical manifestations of an acute allergic process. |
| first_indexed | 2024-03-12T04:47:25Z |
| format | Article |
| id | doaj.art-e94a991a445641ae9a75afbcfe3a0c56 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T04:47:25Z |
| publishDate | 2016-08-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-e94a991a445641ae9a75afbcfe3a0c562023-09-03T09:26:58Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352016-08-0115326827210.15690/vsp.v15i3.15641601Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective StudyElena I. Danilova0Oksana Yu. Trusova1Anton N. Roschupkin2Zinaida A. Veterkova3Ekaterina I. Golovacheva4Tatiana N. Ignatova5Оренбургский государственный медицинский университет, Оренбург, Российская ФедерацияОренбургский государственный медицинский университет, Оренбург, Российская ФедерацияОренбургский государственный медицинский университет, Оренбург, Российская ФедерацияОренбургский государственный медицинский университет, Оренбург, Российская ФедерацияОренбургский государственный медицинский университет, Оренбург, Российская ФедерацияОренбургский государственный медицинский университет, Оренбург, Российская ФедерацияBackground: Atopic dermatitis (AD) is an important issue, significance of which is determined by the incidence increase, chronic, relapsing course of the disease, and poor treatment efficacy.Objective: Our aim was to study clinical efficacy of enterosorbent based on pectin, inulin and fennel extract in combined AD treatment in children.Methods: «Case-control» prospective study included children from 3 to 11 years admitted to hospital with moderate AD.Results: 20 patients included in the study took enterosorbent in addition to the basic therapy, 20 patients had only basic therapy. Compared groups were matched by sex, age, and AD severity by SCORAD scale. Cutaneous AD manifestations in the main group were arrested average over the period of 3.4 ± 1.2 days, in the control group — of 4.7 ± 1.5 days (p < 0.001), skin itch — of 4.0 ± 0.9 and 6.8 ± 1.4 days (p < 0.001), skin dryness — of 9.8 ± 1.1 and 12.3 ± 1.6 days, respectively (р < 0.001).Conclusion: Adding enterosorbent containing pectin, inulin and fennel extract to the basic therapy of moderate AD makes it easier to arrest the clinical manifestations of an acute allergic process.https://vsp.spr-journal.ru/jour/article/view/1639детиатопический дерматитэнтеросорбенты |
| spellingShingle | Elena I. Danilova Oksana Yu. Trusova Anton N. Roschupkin Zinaida A. Veterkova Ekaterina I. Golovacheva Tatiana N. Ignatova Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study Вопросы современной педиатрии дети атопический дерматит энтеросорбенты |
| title | Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study |
| title_full | Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study |
| title_fullStr | Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study |
| title_full_unstemmed | Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study |
| title_short | Efficacy of Enterosorbent Based on Pectin, Inulin and Fennel Extract in Treating Children with Atopic Dermatitis: «Case-Control» Prospective Study |
| title_sort | efficacy of enterosorbent based on pectin inulin and fennel extract in treating children with atopic dermatitis case control prospective study |
| topic | дети атопический дерматит энтеросорбенты |
| url | https://vsp.spr-journal.ru/jour/article/view/1639 |
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