A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area
Abstract Objective Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. We conducted a pilot randomized controlled trial (RCT...
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| Format: | Article |
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BMC
2021-01-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-020-05417-3 |
| _version_ | 1819320546557427712 |
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| author | Elexis C. Kierstead Emily Harvey Denisse Sanchez Kimberly Horn Lorien C. Abroms Freya Spielberg Cassandra A. Stanton Charles Debnam Amy M. Cohn Tiffany Gray Manya Magnus Minal Patel Raymond Niaura Jessica L. Elf |
| author_facet | Elexis C. Kierstead Emily Harvey Denisse Sanchez Kimberly Horn Lorien C. Abroms Freya Spielberg Cassandra A. Stanton Charles Debnam Amy M. Cohn Tiffany Gray Manya Magnus Minal Patel Raymond Niaura Jessica L. Elf |
| author_sort | Elexis C. Kierstead |
| collection | DOAJ |
| description | Abstract Objective Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. We conducted a pilot randomized controlled trial (RCT) to evaluate a tailored smoking cessation intervention based on the minority stress model. We compared standard of care counseling (SOC) to a tailored intervention (TI) including one face-to-face counseling session incorporating cognitive behavioral therapy to build resilience, and 30 days of 2-way text messaging. Results The primary outcome was smoking cessation. Secondary outcomes included cigarettes per day (CPD), exhaled carbon monoxide (CO), and cessation self-efficacy. A total of 25 participants were enrolled (TI:11, SOC:14), and 2 were lost to follow-up. There were no significant differences in quit rates between study groups. However, there was a significantly greater decrease in CPD in the TI versus SOC (13.5 vs. 0.0, p-value:0.036). Additionally, self-efficacy increased in both groups (TI p-value:0.012, SOC p-value:0.049) and CO decreased in both groups (TI p-value: < 0.001, SOC p-value:0.049). This intervention shows promise to support smoking cessation among PLWH. A larger study is needed to fully evaluate the efficacy of this approach. Clinical trial: Trial Registration: Retrospectively registered (10/20/2020) NCT04594109. |
| first_indexed | 2024-12-24T11:21:18Z |
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| id | doaj.art-e94b0b099fc94c54a1e2beba196f7668 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-24T11:21:18Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-e94b0b099fc94c54a1e2beba196f76682022-12-21T16:58:14ZengBMCBMC Research Notes1756-05002021-01-011411710.1186/s13104-020-05417-3A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan areaElexis C. Kierstead0Emily Harvey1Denisse Sanchez2Kimberly Horn3Lorien C. Abroms4Freya Spielberg5Cassandra A. Stanton6Charles Debnam7Amy M. Cohn8Tiffany Gray9Manya Magnus10Minal Patel11Raymond Niaura12Jessica L. Elf13Schroeder Institute, Truth InitiativeThe Henry M. Jackson Foundation for the Advancement of Military MedicineSchroeder Institute, Truth InitiativeCarilion Fralin Biomedical Research Institute at VTC, Virginia Polytechnic Institute and State UniversityDepartment of Prevention and Community Health, Milken Institute School of Public Health, The George Washington UniversityDepartment of Population Health, Dell Medical School, University of TexasBehavioral Health and Health Policy PracticeCommunity Wellness AllianceDepartment of Pediatrics, University of Oklahoma College of MedicineDepartment of Community Health Administration, Department of HealthDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington UniversitySchroeder Institute, Truth InitiativeDepartment of Social and Behavioral Sciences, School of Global Public Health, New York UniversityDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine & Biomedical SciencesAbstract Objective Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. We conducted a pilot randomized controlled trial (RCT) to evaluate a tailored smoking cessation intervention based on the minority stress model. We compared standard of care counseling (SOC) to a tailored intervention (TI) including one face-to-face counseling session incorporating cognitive behavioral therapy to build resilience, and 30 days of 2-way text messaging. Results The primary outcome was smoking cessation. Secondary outcomes included cigarettes per day (CPD), exhaled carbon monoxide (CO), and cessation self-efficacy. A total of 25 participants were enrolled (TI:11, SOC:14), and 2 were lost to follow-up. There were no significant differences in quit rates between study groups. However, there was a significantly greater decrease in CPD in the TI versus SOC (13.5 vs. 0.0, p-value:0.036). Additionally, self-efficacy increased in both groups (TI p-value:0.012, SOC p-value:0.049) and CO decreased in both groups (TI p-value: < 0.001, SOC p-value:0.049). This intervention shows promise to support smoking cessation among PLWH. A larger study is needed to fully evaluate the efficacy of this approach. Clinical trial: Trial Registration: Retrospectively registered (10/20/2020) NCT04594109.https://doi.org/10.1186/s13104-020-05417-3HIV/AIDSTobaccoCessationBehavioral healthMinority health |
| spellingShingle | Elexis C. Kierstead Emily Harvey Denisse Sanchez Kimberly Horn Lorien C. Abroms Freya Spielberg Cassandra A. Stanton Charles Debnam Amy M. Cohn Tiffany Gray Manya Magnus Minal Patel Raymond Niaura Jessica L. Elf A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area BMC Research Notes HIV/AIDS Tobacco Cessation Behavioral health Minority health |
| title | A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area |
| title_full | A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area |
| title_fullStr | A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area |
| title_full_unstemmed | A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area |
| title_short | A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area |
| title_sort | pilot randomized controlled trial of a tailored smoking cessation program for people living with hiv in the washington d c metropolitan area |
| topic | HIV/AIDS Tobacco Cessation Behavioral health Minority health |
| url | https://doi.org/10.1186/s13104-020-05417-3 |
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