Essential Oils of Lamiaceae Family Plants as Antifungals
The incidence of fungal infections has been steadily increasing in recent years. Systemic mycoses are characterized by the highest mortality. At the same time, the frequency of infections caused by drug-resistant strains and new pathogens e.g., <i>Candida auris</i> increases. An alternat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/10/1/103 |
| _version_ | 1818145157868945408 |
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| author | Tomasz M. Karpiński |
| author_facet | Tomasz M. Karpiński |
| author_sort | Tomasz M. Karpiński |
| collection | DOAJ |
| description | The incidence of fungal infections has been steadily increasing in recent years. Systemic mycoses are characterized by the highest mortality. At the same time, the frequency of infections caused by drug-resistant strains and new pathogens e.g., <i>Candida auris</i> increases. An alternative to medicines may be essential oils, which can have a broad antimicrobial spectrum. Rich in the essential oils are plants from the Lamiaceae family. In this review are presented antifungal activities of essential oils from 72 Lamiaceae plants. More than half of these have good activity (minimum inhibitory concentrations (MICs) < 1000 µg/mL) against fungi. The best activity (MICs < 100) have essential oils from some species of the genera <i>Clinopodium</i>, <i>Lavandula</i>, <i>Mentha</i>, <i>Thymbra</i>, and <i>Thymus</i>. In some cases were observed significant discrepancies between different studies. In the review are also shown the most important compounds of described essential oils. To the chemical components most commonly found as the main ingredients include β-caryophyllene (41 plants), linalool (27 plants), limonene (26), β-pinene (25), 1,8-cineole (22), carvacrol (21), α-pinene (21), p-cymene (20), γ-terpinene (20), and thymol (20). |
| first_indexed | 2024-12-11T11:59:00Z |
| format | Article |
| id | doaj.art-e94d23e8198449cb9c1f491c63fce45a |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-12-11T11:59:00Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-e94d23e8198449cb9c1f491c63fce45a2022-12-22T01:08:08ZengMDPI AGBiomolecules2218-273X2020-01-0110110310.3390/biom10010103biom10010103Essential Oils of Lamiaceae Family Plants as AntifungalsTomasz M. Karpiński0Department of Medical Microbiology, Poznań University of Medical Sciences, Wieniawskiego 3, 61-712 Poznań, PolandThe incidence of fungal infections has been steadily increasing in recent years. Systemic mycoses are characterized by the highest mortality. At the same time, the frequency of infections caused by drug-resistant strains and new pathogens e.g., <i>Candida auris</i> increases. An alternative to medicines may be essential oils, which can have a broad antimicrobial spectrum. Rich in the essential oils are plants from the Lamiaceae family. In this review are presented antifungal activities of essential oils from 72 Lamiaceae plants. More than half of these have good activity (minimum inhibitory concentrations (MICs) < 1000 µg/mL) against fungi. The best activity (MICs < 100) have essential oils from some species of the genera <i>Clinopodium</i>, <i>Lavandula</i>, <i>Mentha</i>, <i>Thymbra</i>, and <i>Thymus</i>. In some cases were observed significant discrepancies between different studies. In the review are also shown the most important compounds of described essential oils. To the chemical components most commonly found as the main ingredients include β-caryophyllene (41 plants), linalool (27 plants), limonene (26), β-pinene (25), 1,8-cineole (22), carvacrol (21), α-pinene (21), p-cymene (20), γ-terpinene (20), and thymol (20).https://www.mdpi.com/2218-273X/10/1/103labiataefungi<i>aspergillus</i>cryptococcuspenicilliumdermatophytesβ-caryophyllenesesquiterpenemonoterpenesminimal inhibitory concentration (mic) |
| spellingShingle | Tomasz M. Karpiński Essential Oils of Lamiaceae Family Plants as Antifungals Biomolecules labiatae fungi <i>aspergillus</i> cryptococcus penicillium dermatophytes β-caryophyllene sesquiterpene monoterpenes minimal inhibitory concentration (mic) |
| title | Essential Oils of Lamiaceae Family Plants as Antifungals |
| title_full | Essential Oils of Lamiaceae Family Plants as Antifungals |
| title_fullStr | Essential Oils of Lamiaceae Family Plants as Antifungals |
| title_full_unstemmed | Essential Oils of Lamiaceae Family Plants as Antifungals |
| title_short | Essential Oils of Lamiaceae Family Plants as Antifungals |
| title_sort | essential oils of lamiaceae family plants as antifungals |
| topic | labiatae fungi <i>aspergillus</i> cryptococcus penicillium dermatophytes β-caryophyllene sesquiterpene monoterpenes minimal inhibitory concentration (mic) |
| url | https://www.mdpi.com/2218-273X/10/1/103 |
| work_keys_str_mv | AT tomaszmkarpinski essentialoilsoflamiaceaefamilyplantsasantifungals |