Kinetic modeling of H2O2 dynamics in the mitochondria of HeLa cells.
Hydrogen peroxide (H2O2) promotes a range of phenotypes depending on its intracellular concentration and dosing kinetics, including cell death. While this qualitative relationship has been well established, the quantitative and mechanistic aspects of H2O2 signaling are still being elucidated. Mitoch...
Main Authors: | Kassi T Stein, Sun Jin Moon, Athena N Nguyen, Hadley D Sikes |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-09-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008202 |
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