Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues

Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues

Abstract Background Nicotinic acetylcholine receptors (nAChRs) play an important role in cellular physiology and human nicotine dependence, and are closely associated with many human diseases including cancer. For example, previous studies suggest that nAChRs can re-wire gene regulatory networks in...

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Bibliographic Details
Main Authors: Bo Zhang, Pamela Madden, Junchen Gu, Xiaoyun Xing, Savita Sankar, Jennifer Flynn, Kristen Kroll, Ting Wang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Genomics
Subjects:
Nicotinic acetylcholine receptors
CHRNA4
Epigenetics
Tissue-specificity
Liver
Evolution
Online Access:http://link.springer.com/article/10.1186/s12864-017-3813-4

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