Apoptosis and autophagy markers predict survival in neoadjuvant treated oesophageal adenocarcinoma patients

Apoptosis and autophagy markers predict survival in neoadjuvant treated oesophageal adenocarcinoma patients

Abstract Background Less than 20 % of patients with resectable oesophageal adenocarcinoma obtain a pathological response following neoadjuvant chemotherapy. Studies using oesophageal cancer cell lines have shown that drug sensitive tumour cells undergo apoptosis in response to drug treatment, wherea...

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Bibliographic Details
Main Authors: Shereen El Mashed, Tracey R. O’Donovan, Elaine Kay, Anthony O’Grady, Damian McManus, Richard C. Turkington, Sharon L. McKenna
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Cancer
Subjects:
Caspase-3
autophagy
LC3B
oesophageal adenocarcinoma
predictive biomarkers
Online Access:https://doi.org/10.1186/s12885-022-09981-8

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