Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study

Abstract Background Retention of HIV Exposed Infants (HEIs) in care ensures adequate care. Data on retention of HEIs at large referral hospitals in Uganda is limited. We investigated the retention level of HEIs and associated factors. Methods We conducted a retrospective cohort study on 352 HEIs in...

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Main Authors: Pontius Apangu, Jonathan Izudi, Francis Bajunirwe, Edgar Mulogo, Vincent Batwala
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-019-6754-9
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author Pontius Apangu
Jonathan Izudi
Francis Bajunirwe
Edgar Mulogo
Vincent Batwala
author_facet Pontius Apangu
Jonathan Izudi
Francis Bajunirwe
Edgar Mulogo
Vincent Batwala
author_sort Pontius Apangu
collection DOAJ
description Abstract Background Retention of HIV Exposed Infants (HEIs) in care ensures adequate care. Data on retention of HEIs at large referral hospitals in Uganda is limited. We investigated the retention level of HEIs and associated factors. Methods We conducted a retrospective cohort study on 352 HEIs in care (January 2014 and April 2015) at Arua Regional Referral Hospital, North-western Uganda. Electronic medical data were retrieved and analyzed with Stata. Chi-square, Fisher’s exact, and Students t-tests were used for bivariate analysis. Logistic regression was performed to determine factors independently associated with retention. Results 236 (67.0%) HEIs were delivered in a health facility and 306 (86.9%) received Nevirapine prophylaxis from birth until 6-weeks. Of mothers, 270 (76.7%) were 25–46 years, 202 (57.4%) attended antenatal care (ANC) at recent pregnancy, and 328 (93.2%) were on life-long anti-retroviral therapy. At 18-months, 277 (78.7%) HEIs were retained in care. Maternal age (25–46 years) (Adjusted Odds Ratio (AOR), 2.32; 95% CI, 1.32–4.06), ANC attendance during recent pregnancy (AOR, 2.01; 95% CI, 1.19–4.3.41) and Nevirapine prophylaxis initiation from birth until 6-weeks (AOR, 3.07; 95% CI, 1.50–6.26) were associated with retention. Conclusion Retention was suboptimal. Older maternal age, ANC visits at last pregnancy, and timely NVP initiation increased retention.
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spelling doaj.art-e958d0fd9da54f0ca174be51ac2c87d12022-12-21T19:06:44ZengBMCBMC Public Health1471-24582019-04-011911810.1186/s12889-019-6754-9Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort studyPontius Apangu0Jonathan Izudi1Francis Bajunirwe2Edgar Mulogo3Vincent Batwala4Department of Community Health, Faculty of Medicine, Mbarara University of Science and TechnologyDepartment of Community Health, Faculty of Medicine, Mbarara University of Science and TechnologyDepartment of Community Health, Faculty of Medicine, Mbarara University of Science and TechnologyDepartment of Community Health, Faculty of Medicine, Mbarara University of Science and TechnologyDirectorate of Research and Graduate Training, Mbarara University of Science and TechnologyAbstract Background Retention of HIV Exposed Infants (HEIs) in care ensures adequate care. Data on retention of HEIs at large referral hospitals in Uganda is limited. We investigated the retention level of HEIs and associated factors. Methods We conducted a retrospective cohort study on 352 HEIs in care (January 2014 and April 2015) at Arua Regional Referral Hospital, North-western Uganda. Electronic medical data were retrieved and analyzed with Stata. Chi-square, Fisher’s exact, and Students t-tests were used for bivariate analysis. Logistic regression was performed to determine factors independently associated with retention. Results 236 (67.0%) HEIs were delivered in a health facility and 306 (86.9%) received Nevirapine prophylaxis from birth until 6-weeks. Of mothers, 270 (76.7%) were 25–46 years, 202 (57.4%) attended antenatal care (ANC) at recent pregnancy, and 328 (93.2%) were on life-long anti-retroviral therapy. At 18-months, 277 (78.7%) HEIs were retained in care. Maternal age (25–46 years) (Adjusted Odds Ratio (AOR), 2.32; 95% CI, 1.32–4.06), ANC attendance during recent pregnancy (AOR, 2.01; 95% CI, 1.19–4.3.41) and Nevirapine prophylaxis initiation from birth until 6-weeks (AOR, 3.07; 95% CI, 1.50–6.26) were associated with retention. Conclusion Retention was suboptimal. Older maternal age, ANC visits at last pregnancy, and timely NVP initiation increased retention.http://link.springer.com/article/10.1186/s12889-019-6754-9RetentionHIV exposed infantsEarly infant diagnosis of HIVUganda
spellingShingle Pontius Apangu
Jonathan Izudi
Francis Bajunirwe
Edgar Mulogo
Vincent Batwala
Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
BMC Public Health
Retention
HIV exposed infants
Early infant diagnosis of HIV
Uganda
title Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
title_full Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
title_fullStr Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
title_full_unstemmed Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
title_short Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study
title_sort retention of hiv exposed infants in care at arua regional referral hospital uganda a retrospective cohort study
topic Retention
HIV exposed infants
Early infant diagnosis of HIV
Uganda
url http://link.springer.com/article/10.1186/s12889-019-6754-9
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