Description, Staging and Quantification of Pulmonary Artery Angiophagy in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension

Description, Staging and Quantification of Pulmonary Artery Angiophagy in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension

Angiophagy has been described as a non-fibrinolytic mechanism of pulmonary artery (PA) patency restoration after distal (<50 µm in diameter) pulmonary embolism in mice. We hypothesized that angiophagy could achieve muscularized PA patency restoration after pulmonary embolism in piglets and humans...

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Bibliographic Details
Main Authors: Frédéric Perros, Maria-Rosa Ghigna, Fanny Loisel, Denis Chemla, Benoit Decante, Vincent de Montpreville, David Montani, Marc Humbert, Elie Fadel, Olaf Mercier, David Boulate
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
pulmonary embolism
angiophagy
pulmonary artery
remodeling
pathology
animal model
Online Access:https://www.mdpi.com/2227-9059/8/11/493

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