DNMT family induces down-regulation of NDRG1 via DNA methylation and clinicopathological significance in gastric cancer

DNMT family induces down-regulation of NDRG1 via DNA methylation and clinicopathological significance in gastric cancer

Background Aberrant DNA methylation of tumor suppressor genes is a common event in the development and progression of gastric cancer (GC). Our previous study showed NDRG1, which could suppress cell invasion and migration, was frequently down-regulated by DNA methylation of its promoter in GC. Purpos...

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Bibliographic Details
Main Authors: Xiaojing Chang, Jinguo Ma, Xiaoying Xue, Guohui Wang, Tianfang Yan, Linlin Su, Xuetao Han, Huandi Zhou, Liubing Hou
Format: Article
Language:English
Published: PeerJ Inc. 2021-09-01
Series:PeerJ
Subjects:
Tumor suppressor gene
NDRG1
DNMT
DNA methylation
Metastasis
Gastric cancer
Online Access:https://peerj.com/articles/12146.pdf

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