The Immunity Protection of Central Nervous System Induced by Pseudorabies Virus DelgI/gE/TK in Mice

The Immunity Protection of Central Nervous System Induced by Pseudorabies Virus DelgI/gE/TK in Mice

Based on a variant strain, we constructed a gE/gI/TK-deleted pseudorabies virus (PRV). A total of 18 female mice were randomized to a vaccination group to receive PRV XJ delgE/gI/TK, a vehicle group to receive Dulbecco’s modified Eagle’s medium, and a mock group to confirm the protection of PRV delg...

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Bibliographic Details
Main Authors: Lei Xu, Jian-feng Wei, Jun Zhao, Si-yao Xu, Feng-qin Lee, Min-cai Nie, Zhi-wen Xu, Yuan-cheng Zhou, Ling Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
Subjects:
pseudorabies virus
neurological damage
intestinal immunity
blood–brain barrier
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.862907/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.862907/full

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